Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2000-01-27
2008-10-14
Ouspenski, Ilia (Department: 1644)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C530S387300, C530S387900, C530S388100, C530S388200, C530S388220, C424S130100, C424S133100, C424S135100, C424S136100, C424S139100
Reexamination Certificate
active
07435796
ABSTRACT:
Novel polypeptides which comprise a receptor-ligand pair involved in T-cell activation are disclosed. Nucleic acid molecules encoding said polypeptides, and vectors and host cells for expressing same are also disclosed. The polypeptides, or agonists and antagonists thereof, are used to treat T-cell mediated disorders.
REFERENCES:
patent: 3773919 (1973-11-01), Boswell et al.
patent: 4619794 (1986-10-01), Hauser
patent: 4816567 (1989-03-01), Cabilly et al.
patent: 4892538 (1990-01-01), Aebischer et al.
patent: 4970154 (1990-11-01), Chang
patent: 5011472 (1991-04-01), Aebischer et al.
patent: 5106627 (1992-04-01), Aebischer et al.
patent: 5580756 (1996-12-01), Linsley et al.
patent: 5593875 (1997-01-01), Wurm et al.
patent: 5653975 (1997-08-01), Baetge et al.
patent: 5676954 (1997-10-01), Brigham
patent: 6521749 (2003-02-01), Ling et al.
patent: 7030225 (2006-04-01), Tamatani et al.
patent: 7045615 (2006-05-01), Tamantani et al.
patent: 7112655 (2006-09-01), Tamantani et al.
patent: 7125551 (2006-10-01), Kroczek
patent: 7132099 (2006-11-01), Kroczek
patent: 7196175 (2007-03-01), Tamantani et al.
patent: 7217792 (2007-05-01), Tamantani et al.
patent: 7226909 (2007-06-01), Tamantani et al.
patent: 7247612 (2007-07-01), Tamantani et al.
patent: 7259147 (2007-08-01), Tamantani et al.
patent: 7259247 (2007-08-01), Kroczek
patent: 7279560 (2007-10-01), Tamantani et al.
patent: 7294473 (2007-11-01), Tamantani et al.
patent: 7306800 (2007-12-01), Kroczek
patent: 2002/0115831 (2002-08-01), Tamatani et al.
patent: 2002/0151685 (2002-10-01), Tamatani et al.
patent: 2002/0156242 (2002-10-01), Tamatani et al.
patent: 2002/0177191 (2002-11-01), Kroczek
patent: 2002/0182667 (2002-12-01), Kroczek
patent: 2003/0083472 (2003-05-01), Tamatani et al.
patent: 2004/0054158 (2004-03-01), Ling et al.
patent: 2004/0073012 (2004-04-01), Tamatani et al.
patent: 2004/0120945 (2004-06-01), Tamatani et al.
patent: 2004/0132658 (2004-07-01), Tamatani et al.
patent: 2004/0146506 (2004-07-01), Tamatani et al.
patent: 2004/0151669 (2004-08-01), Tamatani et al.
patent: 2004/0151718 (2004-08-01), Tamatani et al.
patent: 2004/0151720 (2004-08-01), Tamatani et al.
patent: 2004/0229788 (2004-11-01), Tamatani et al.
patent: 2005/0261489 (2005-11-01), Kroczek
patent: 2006/0099635 (2006-05-01), Ling et al.
patent: 31399/84 (1986-09-01), None
patent: 0 133 988 (1985-03-01), None
patent: 0 058481 (1986-10-01), None
patent: 0 088 046 (1987-12-01), None
patent: 0 143 949 (1988-10-01), None
patent: 0 154 316 (1989-09-01), None
patent: 0 036 676 (1990-09-01), None
patent: 0 401 384 (1996-03-01), None
patent: 0 984 023 (2000-08-01), None
patent: 0 984 023 (2001-08-01), None
patent: 1 125 585 (2001-08-01), None
patent: 1 502 920 (2005-02-01), None
patent: 1 502 920 (2005-02-01), None
patent: WO 91/10425 (1991-07-01), None
patent: WO 95/11308 (1995-04-01), None
patent: WO 96/40958 (1996-12-01), None
patent: WO 98/38216 (1998-09-01), None
patent: WO 99/15553 (1999-04-01), None
patent: WO 00/46240 (2000-08-01), None
patent: WO 01/12658 (2001-02-01), None
patent: WO 01/12658 (2001-02-01), None
patent: WO 01/21796 (2001-03-01), None
Coleman et al. Research in Immunology, 1994; 145(1): 33-36.
Abaza et al. Journal of Protein Chemistry, vol. 11, No. 5, 1992, pp. 433-444.
Lederman et al. Molecular Immunology 28: 1171-1181, 1991.
Li et al. PNAS 77: 3211-3214, 1980.
Ngo et al.; in The Protein Folding Problem and Tertiary Structure Prediction, 1994, Merz et al., (ed.), Birkhauser, Boston, MA, pp. 433 and 492-495.
Riley et al.: Blood, 2005, 105: 13-21.
Blazar et al., J. Immunol., 1996, 157: 3250-3259.
Freeman et al., “Cloning of B7-2: A CTLA-4 Counter-Receptor That Costimulates Human T Cell Proliferation”, Science 262, 909-911 (1993).
Ling et al., “Cutting Edge: Identification of GL50, a Novel B7-Line Protein That Functionally Binds to ICOS Receptor,”Journal of Immunology, 164(4):1653-1657 (2000).
Tafuri et al., “ICOS is Essential for Effective T-Helper-cell responses,”Nature, 409:105-109 (2001).
Wang et al., “Costimulation of T cells by B7-H2, a B7-like Molecule that Binds ICOS,”Blood, 96(8):2808-2813 (2000).
Yoshinaga et al., “T-cell Co-stimulation Through B7RP-1 and ICOS,”Nature, 402:827-832 (1999).
Altschul et al., “Basic Local Alignment Search Tool”, J. Mol. Biol. 215, 403-410 (1990).
Aruffo and Seed, “Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system”, Proc. Natl. Acad. Sci. 84, 8573-8577 (1987).
Ausubel et al., Current Protocols in Molecular Biology, Green Pub. and Wiley and Sons, NY (1994) Table of Contents.
Brunet et al., “A new member of the immunoglobulin superfamily—CTLA-4”, Nature 328, 267-270 (1987).
Carillo et al., “The Multiple Sequence Alignment Problem in Biology”, SIAM J. Applied Math. 48, 1073 (1988).
Dariavach et al., “Human Ig superfamily CTLA-4 gene: chromosomal localization and identity of protein sequence between murine and human CTLA-4 cytoplasmic domains”, Eur. Jour. Immun. 18, 1901-1905 (1988).
Dayhoff et al., “A Model of Evolutionary Change in Proteins”, Atlas of Protein Sequence and Structure, vol. 5, supp. 3 (1978).
Devereux et al., “A comprehensive set of sequence analysis programs for the VAX”, Nucleic Acids Research 12(1), 387 (1984).
Engels et al., “Gene Synthesis”, Angew. Chem. Intl. Ed. 28, 716-734 (1989).
Eppstein et al., “Biological activity of liposome-encapsulated murine interferon γ is mediated by a cell membrane receptor”, Proc. Natl. Acad. Sci. USA, 82, 3688-3692 (1985).
Francis, “Protein modification and fusion proteins”, Focus on Growth Factors 3, 4-10 (1992).
Freeman et al., “B7, a New Member of the Ig Superfamily with Unique Expression on Activated and Neoplastic B Cells”, J. Immunology 143, 2714-2722 (1989).
Freeman et al., Structure, Expression, and T Cell Costimulatory Activity of the Murine Homologue of the Human B Lymphocyte Jour. Expt. Med. 174, 625-31 (1991).
Freeman et al., “Murine B7-2, an Alternative CTLA4 Counter-receptor that Costimulates T Cell Proliferation and Interleukin 2 Production”, Jour. Expt. Med. 178, 2185-2192 (1993).
Gennaro, Remington's Pharmaceutical Sciences, 18th Edition, ed., Mack Publishing Company (1990) Table of Contents.
Gribskov et al., Sequence Analysis Primer, eds., M. Stockton Press, New York, 1991 Table of Contents.
Griffin et al., Computer Analysis of Sequence Data, Part 1, eds., Humana Press, New Jersey, 1994 Table of Contents.
Gross et al., “The Murine Homologue of the T Lymphocyte Antigen CD28”, J. Immun. 144, 3201-3210 (1990).
Henikoff, “Amino acid substitution matrices from protein blocks”, PNAS, USA 89, 10915-10919 (1992).
Hoogenboom et al., “By-passing Immunisation”, J. Mol. Biol. 227, 381 (1991).
Houghten et al., “General method for the rapid solid-phase synthesis of large numbers of peptides: Specificity of antigen-antibody interaction at the level of individual amino acids”, Proc Natl Acad. Sci. USA 82, 5132 (1985).
Hutloff et al., “ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28”, Nature 397, 263-266 (1999).
Jakobovits et al., “Germ-line transmission and expression of a human-derived yeast artificial chromosome”, Nature 362, 255-258 (1993).
Jakobovits et al., “Analysis of homozygous mutant chimeric mice: Deletion of the immunoglobulin heavy-chain joining region blocks B-cell development and antibody production”, Proc. Natl. Acad. Sci. 90, 2551-2555 (1993).
Jones et al., “Replacing the complementarity-determining regions in a human antibody with those from a mouse”, Nature 321, 522-525 (1986).
Kitts et al., “A Method for Producing Recombinant Baculovirus Expression Vectors at High Frequency”, Biotechniques 14, 810-817 (1993).
Langer et al., “Biocompatibility of polymeric delivery systems for macromo
Amgen Inc.
Ouspenski Ilia
Winter Robert B.
LandOfFree
Antibodies which bind B7RP1 does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antibodies which bind B7RP1, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibodies which bind B7RP1 will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3995723