Antibodies to Tie1 ectodomain

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,...

Reexamination Certificate

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C424S133100, C424S141100, C424S143100, C530S387100, C530S388100, C530S388150, C530S388220

Reexamination Certificate

active

07871610

ABSTRACT:
Tie1 and Tie2 are receptor tyrosine kinase proteins that include a transmembrane domain. Tie1 and Tie2 are present on endothelial cells. This disclosure describes agents, such as antibodies, that bind to Tie1, Tie2, and Ang, including ones that inhibit endothelial cell activity.

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