Antibodies to the HRPII protein of plasmodium falciparum

Details Antibodies to the HRPII protein of plasmodium falciparum Antibodies to the HRPII protein of plasmodium falciparum

1994-05-27

1995-12-26

Feisee, Lila

Chemistry: molecular biology and microbiology

Spore forming or isolating process

5303879, 5303886, 5303911, 4351722, 435 7021, 435 722, 435 34, 436548, C12N 1506, C12N 518, C07K 1620, G01N 3353

Patent

active

054787416

ABSTRACT:
Antibodies which recognize and bind to histidine rich protein II of Plasmodium falciparum. These antibodies exhibit improved specificity and affinity for the antigen which provides enhanced sensitivity in immunoassays. Peptides useful for generation of the antibodies are also provided.

REFERENCES:
patent: 4493795 (1985-01-01), Nestor et al.
patent: 5130416 (1992-07-01), Wellems et al.
Howard et al., J. Cell Biol. 103, 1269-77, 1986.
Rock et al., Parasitology, 95, 209-227, 1987.
Panton et al., Molec. Biochem. Parasitology, 35, 149-60, 1989.
Suppl. to Amer. J. Trop. Med. Hyg. 45(3):248-9, 1991.
Knapp et al. Behring Inst. Mitt. 82, 349-59, 1988.
Wellems et al. Cell 49, 633-42, 1987.
Enzyme-Immunoassay Ed. Edward Maggio Clark and Engvall 1987, pp. 167-179.
Journal of Experimental Medicine vol. 160 1984 pp. 208-221.
Waldman Science vol. 252 p. 1657 1991.

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