Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1995-05-18
1998-10-13
Feisee, Lila
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
5303871, 5303879, 5303881, 5303896, C07K 1624
Patent
active
058213414
ABSTRACT:
The present invention relates to a soluble form of intercellular adhesion molecule (sICAM-1) and purified and isolated human sICAM-1, and antibodies thereto. This invention also relates to a purified and isolated DNA sequence encoding sICAM-1. The extracellular domain of sICAM-1 and insoluble ICAM-1 are substantially the same. ICAM-1 is involved in the process through which lymphocytes attach to cellular substrates during inflammation and serves as the major human rhinovirus receptor (HRR). sICAM-1 therefore has both the property of reducing immune inflammation and inhibiting infection of rhinovirus and Coxsackie A virus.
REFERENCES:
patent: 5235049 (1993-08-01), McClelland et al.
Greve Jeffrey M.
McClelland Alan
Bayer Corporation
Feisee Lila
Gambel Phillip
LandOfFree
Antibodies to sICAM-1 does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antibodies to sICAM-1, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibodies to sICAM-1 will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-314108