Antibodies to receptors for human interleukin-12

Details Antibodies to receptors for human interleukin-12 Antibodies to receptors for human interleukin-12

1997-08-20

1998-12-22

Draper, Garnette D.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

53038822, 4241431, 435 7021, C07K 1628

Patent

active

058521763

ABSTRACT:
Antibodies to human IL-12 beta 2 receptor protein or an IL-12 receptor complex, the complex comprising the beta1 receptor protein complexed with a beta2 receptor protein, which complex is capable of binding to human IL-12 with high affinity.

REFERENCES:
patent: 5536657 (1996-07-01), Chua et al.
Chizzonite et al. Cytokine 6(5) 1994, p. A82a.
Presky et al, Res Immunol 146, 1995, pp. 439-445.
Chizzonite et al, J. Immunol. 147(5) 1991, pp. 1548-1556.
Meajer et al, Lancet 350, 1997, pp. 1596-1597.
Marth et al, Gastroenterology 110(4) 1996, p. A958.
Gately, M.K. et al., 1991, J. Immunol. 147:874.
Kobayashi, M., et al., 1989, J. Exp. Med. 170:827.
Stern, A.S. et al., 1990, Proc. Natl. Acad. Sci. USA 87:6808.
Gately, M.K., 1992, Cell Immunology 143:127.
Chan, S.H. et al., 1991, J. Exp. Med. 173:869.
Manetti, R., et al., 1993, J. Exp. Med. 177:1199.
Hsieh, C.S. et al., 1993, Science 260:547.
Chizzonite, R., et al., 1992, J. Immunol. 148:3117.
Desai, B., et al., J. Immunol, 1992, 148:3125.
Desai, B., et al., 1993, J. Immunol. 150:207A.
Chizzonite, R., et al., 1994, Cytokine 6(5):A82a.
Chua, A., et al., 1994, J. Immunology 153:128.
Stahl & Yancopoulos, 1993, Cell 74:587.
Charnow, S.M., et al., Trends in Biotechnology vol. 14 52-60 (1996).
M.O. Dayhoff, et al., Methods Enzymology 91:524 (1983).
U. Gubler, et al., 1991, Proc. Natl. Acad. Sci USA 88:4143.
H.W. Lahm et al. 1985, J. Chromatog. 326:357.
S. Mizushima & S. Nagata, Nucl. Acids Res. 1990 18:5322.
S. Grant. et al. 1990, Proc. Natl. Acad. Sci. USA 87:4645.
Gately, et al., J. Natl. Cancer Inst. 69 1245 (1982).
P. Chomczynski & N. Sacchi, Anal. Biochem. 162: 156, 1987.
K. Kuribayashi et al. Nucl. Acids Res. Symposium Series 19:61, 1988.
U. Gubler & A. Chua, Essential Molecular Biology vol. II, T.A. Brown, editor pp. 39-56 TRL Press 1991.
A. Aruffo & B. Seed, Proc. Natl. Acad. Sci (USA) 94, 8573, 1987.
Hara & Miyajima 1992, EMBO 11:1875.
Grunstein & Hogness, Molecular Cloning Proc. Nat. Acad. Sci. USA 72:3961 (1975).
McPherson J., 1985, Pharmacol Methods, 14:213.
Palacios R., et al., 1985, Cell 41:727.
Giordano, T. J. et al., 1990, Gene 88:285.
vonHeijne G., 1986, Nucl. Acids Research 14;4683.
Presky, D., et al., Res. Immunol. 146 439-445 (1995).
Ellison et al., Nucl. Acid Res. 10 4071-4079.
Huck, et al., Nucl. Acid Res 14 1779-1789 (1986).
Presky, et al., PNAS 93(24), pp. 14002-14007 (1996).
Gubler, et al., FASEB J. 10(6), A1326 (1996).
Szabo et al., FASEB J. 10(6), A1310 (1996).

Affiliated with

Also associated with

Rating

Antibodies to receptors for human interleukin-12 does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antibodies to receptors for human interleukin-12, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibodies to receptors for human interleukin-12 will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2049310