Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2005-07-21
2009-10-06
Yaen, Christopher H (Department: 1643)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
Reexamination Certificate
active
07598349
ABSTRACT:
The present invention provides a peptide fragment or a series of peptide fragments having a cell death-inhibitory activity, having the amino acid sequence consisting of 103 amino acid residues at the C-terminal of selenoprotein P, or having said amino acid sequence with one or several amino acid residues therein being deleted, substituted or added, or having a partial sequence of either of the above amino acid sequences, a medicament for treatment comprising said peptide fragment or a series of peptide fragments, an antibody to said peptide fragment or a series of peptide fragments, and a method for screening a cell death-inhibitory activity using said peptide fragment or a series of peptide fragments. The preferable peptide fragment or a series of peptide fragments of the present invention has the amino acid sequences shown in SEQ ID NO: 1 and/or SEQ ID NO: 2 or has a partial sequence thereof.
REFERENCES:
Himeno et al (J. Biol. Chem. 1996; 271(26):15769-15775).
Campbell, A (Monoclonal Antibody Technology; 1984; Elsevier Science Publishing Company: pp. 1-33).
Greenberg S. M., et al., “Characterization of a New Megakaryocytic Cell Line: The Dami Cell”, Blood, vol. 72, No. 6, 1988, pp. 1968-1977.
“Catalog No. 1011391: Nutridoma-HU”, Roche Molecular Biochemicals Catalogue, Online, Oct. 1999.
MacLeod, R.A.F., et al., “Identity of Original and Late Passage Dami Megakaryocytes with HEL Erythroleukemia Cells Shown by Combined Cytogenetics and DNA fingerprinting”, Leukemia, vol. 11, No. 12, Dec. 1997, pp. 2032-2038.
“Using Apoptosis to Screen for Tumour Promoters”, Research Disclosure, Kenneth Mason Publications, vol. 427, No. 57, Nov. 1999.
Masaki Hirashima et al.; Biol. Pharm. Bull., vol. 26, No. 6, pp. 794-798 (2003).
Hill et al., Proc. Natl. Acad. Sci, vol. 90, No. 2, pp. 537-541 (1993).
Akesson et al., Biochim. Biophys. Acta, vol. 1204, No. 2, pp. 243-249 (1994).
Hill et al., J. Nutr. vol. 126, No. 1, pp. 138-145 (1996).
Persson-Moschos et al., Analyst, vol. 120, No. 3, pp. 833-836 (1995).
Arteel et al., Biol. Chem. vol. 379, Nos. 8-9 (Aug.-Sep. 1998).
Craig B. Thompson, Science, vol. 267, Mar. 10, 1995, pp. 1456-1462.
Lixin Zheng et al., Nature, vol. 377, Sep. 28, 1995, pp. 348-351.
Takashi Suda et al., Cell, vol. 75, Dec. 17, 1993, pp. 1169-1178.
A. H. Wyllie, Nature, vol. 284, Apr. 10, 1980, pp. 555-556.
Lawrence H. Boise et al., Cell, vol. 74, Aug. 27, 1993, pp. 597-608.
Laura J. S. Greenlund et al., Neuron, vol. 14, Feb. 1995, pp. 303-315.
Paul A. Sandstrom et al., Proc. Natl. Acad. Sci. USA, vol. 90, May 1993, pp. 4708-4712.
Yoshiro Kayanoki et al., J. Biochem., vol. 119, 1996, pp. 817-822.
Kristina E. Hill et al., Biomedical and Environmental Sciences, vol. 10, 1997, pp. 198-208.
G. Kohler et al., Nature, vol. 256, Aug. 7, 1975, pp. 495-497.
Sheryl M. Greenberg et al., Blood, vol. 72, No. 6, Dec. 1988, pp. 1968-1977.
Kristina E. Hill et al., Proc. Natl. Acad. Sci, USA, vol. 90, Jan. 1993, pp. 537-541.
D. E. Yelton et al., Curr Top Microbiol lmmunol, vol. 81, pp. 1-7, 1978.
Katja Zurbonsen et al., European Journal of Pharmacology, vol. 320, pp. 215-221, 1997.
Rafferty et al. (Biochem J May 15, 1998; 332 (Pt1):231-6).
Dermer (Bio/Tehcnology, 1994, 12:320).
Burgess et al, J of Cell Bio. 111:2129-2138, 1990.
Lazar et al., Molecular and Cellular Biology 8:1247-1252, 1988.
Bowie et al. Science, 247:1306-1310, 1990, p. 1306, col. 2.
Freshney (Culture of Animal Cell, A Manual of Basic Technique, Alan R. Liss, Inc., 1983, New York, p4).
Jun Yan et al.; the Journal of Neuroscience, vol. 18, No. 21, pp. 8682-8691 (Nov. 1,1998).
Hirashima Masaki
Maeda Hiroaki
Nozaki Chikateru
Birch & Stewart Kolasch & Birch, LLP
Juridical Foundation The Chemo-Sero-Therapeutic Research Institu
Yaen Christopher H
LandOfFree
Antibodies to peptide fragments having cell death-inhibitory... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antibodies to peptide fragments having cell death-inhibitory..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibodies to peptide fragments having cell death-inhibitory... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4104508