Antibodies to P-selectin and their uses

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof

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4241331, 4241431, 4241731, 435 724, 435 7021, 4351722, 435316, 435328, 435343, 435346, 5303873, 5303882, 5303887, 5303896, 536 2353, A61K 39395, C07K 1628, C12N 512, C07H 2104

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active

058008152

ABSTRACT:
The present invention relates to compositions and methods for treating inflammation and other pathological conditions using novel blocking P-selectin antibodies that inhibit adhesion of leukocytes to activated platelets and/or to activated vascular endothelium in vivo. Both murine and humanized antibodies are provided.

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