Antibodies to non-shed Muc1 and Muc16, and uses thereof

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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C530S387300, C530S350000, C530S380000, C530S385000, C530S387100, C530S387700, C424S134100, C424S135100, C424S141100, C424S155100, C424S142100, C424S178100, C424S085100, C435S007900, C435S188000, C435S320100, C525S054100

Reexamination Certificate

active

10612090

ABSTRACT:
The present invention relates to antibodies, antibody fragments, conjugates of antibodies and antibody fragments with cytotoxic agents, and hybridomas producing the antibodies and antibody fragments, where the antibodies and antibody fragments recognize extracellular epitopes of plasma membrane proteins that are not released into the extracellular fluid, and to methods for the detection, monitoring and treatment of malignancies such as breast cancer and ovarian cancer using the antibodies, antibody fragments and conjugates.

REFERENCES:
patent: 5776427 (1998-07-01), Thorpe et al.
patent: 5846545 (1998-12-01), Chari et al.
patent: 6166176 (2000-12-01), Radosevich
patent: 6333410 (2001-12-01), Chari et al.
patent: 6340701 (2002-01-01), Chari et al.
patent: 6512096 (2003-01-01), Weiner et al.
patent: 2003/0170237 (2003-09-01), Ni et al.
patent: 2003/0235868 (2003-12-01), Hoogenboom et al.
patent: 2004/0146862 (2004-07-01), Mack et al.
patent: 2005/0053606 (2005-03-01), Kufe et al.
patent: 2005/0064518 (2005-03-01), Albone et al.
patent: WO 96/03502 (1996-02-01), None
patent: WO 01/090197 (2001-11-01), None
patent: WO 02/06317 (2002-01-01), None
patent: WO 02/22685 (2002-03-01), None
patent: WO 02/078598 (2002-10-01), None
patent: WO 03/089451 (2003-10-01), None
Hartman et al (Int. J. Cancer 1999; 82:256-267).
Zrihan-Licht et al (Eur. J. Biochem. 1994; 224:787-795).
Parry et al (Biochem, Biophys. Res. Comm. 2001; 283:715-720).
William E. Paul, M.D. ed., Fundamental Immunology 242 3d ed. 1993.
Colman et al (Research in Immunology 1994, 145:33-36).
Ibragimova and Eade (Biophysical Journal, Oct. 1999, vol. 77, pp. 2191-2198).
Rudikoff et al (Proc. Natl. Acad. Sci. USA 1982 vol. 79 p. 1979).
O'Brien et al,Tumor Biology, 22 (6):348-366 (2001).
Pietersz et al,Vaccine, 18 (19):2059-2071 (2000).
Taylor-Papadimitriou et al,Biochimica et Biophysica ACTA, Molecular Basis of Disease, 1455 (2-3):301-313 (1999).

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