Antibodies to nitrogen derivatives of benzoyl ecgonine antigenic

Details Antibodies to nitrogen derivatives of benzoyl ecgonine antigenic Antibodies to nitrogen derivatives of benzoyl ecgonine antigenic

1975-02-12

1980-04-08

Fagelson, Anna P.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260112R, 2601125R, 260121, 424 1, 424 8, 424 12, 424 85, 424177, C07G 700, G01N 3100, G01N 3316

Patent

active

041972376

ABSTRACT:
Nitrogen derivatives of benzoyl ecgonine and cocaine are provided, particularly amino, diazonium, and diazo derivatives, the compounds finding use either directly or as intermediates for the preparation of reagents for use in immunoassays. Diazo compounds can be coupled with antigenic materials for the preparation of antibodies to benzoyl ecgonine and/or cocaine. The amino group can be combined with active non-oxo-carbonyl compounds to form reagents which find use in immunoassays.

REFERENCES:
patent: 3690834 (1972-09-01), Goldstein
patent: 3852157 (1974-12-01), Rubenstein
patent: 3966764 (1976-06-01), Goldstein
patent: 3975237 (1976-08-01), Rubenstein
patent: 4022878 (1977-05-01), Gross

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