Antibodies to lymphocyte activation antigens and uses therefor

Details Antibodies to lymphocyte activation antigens and uses therefor Antibodies to lymphocyte activation antigens and uses therefor

1998-01-30

2000-05-30

Saunders, David

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 2, 435 721, 435 792, 435 30, 435325, 436518, C12N 100, G01N 33543

Patent

active

060689846

ABSTRACT:
HB15-related lymphocyte activation antigens, and nucleic acid sequences encoding HB15-related antigens are disclosed. Also disclosed are antibodies reactive with HB15.

REFERENCES:
patent: 5098833 (1992-03-01), Lasky et al.
patent: 5316920 (1994-05-01), Tedder et al.
patent: 5766570 (1998-06-01), Tedder et al.
Williams et al., "The Immunoglobulin Superfamily--Domains for Cell Surface Recognition," Ann. Rev. Immunol. 6:381-405 (1988).
Littman et al., "The Isolation and Sequence of the Gene Encoding T8: A Molecule Defining Functional Classes of T-Lymphocytes," Cell 40:237-246 (1985).
Johnson et al., "Striking similarities between antigen receptor J pieces and sequence in the second chain of the murine CD8 antigen," Nature 323:74-76 (1986).
Aruffo et al., "Molecular cloning of two CD7 (T-Cell leukemia antigen) cDNAs by a COS cell expression system," EMBO J. 6:3313-3316 (1987).
Williams et al., "Neuronal Cell Thy-1 Glycoprotein: Homology with Immunoglobulin," Science 216:696-703 (1982).
Aruffo et al., "Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system," Proc. Natl. Acad. Sci. USA 84:8573-8577 (1987).
Brunet et al., "A new member of the immunoglobulin superfamily--CTLA-4," Nature 328:267-270 (1987).
Lemke et al., "Isolation and Sequence of a cDNA Encoding the Major Structural Protein of Peripheral Myelin," Cell 40:501-508 (1985).
Gold et al., "Isolation of cDNA clones encoding the 20K non-glycosylated polypeptide chain of the human T-cell receptor/T3 complex," Nature 321:431-434 (1986).
van den Elsen et al., "Isolation of cDNA clones encoding the 20K T3 glycoprotein of human T-cell receptor complex," Nature 312:413-418 (1984).
Hermanson et al., "B29: A member of the immunoglobulin gene superfamily exclusively expressed on B-lineage cells," Proc. Natl. Acad. Sci USA 85:6890-6894 (1988).
Sakaguchi et al., "B lymphocyte lineage-restricted expression of mb-1, a gene with CD3-like structural properties," EMBO J. 7:3457-3464 (1988).
Turka et al., "CD28 is an inducible T-cell surface antigen that transduces a proliferative signal in CD3.sup.+ mature thymocytes," J. Immunol. 144:1646-1653 (1990).
Harper et al., "CTLA-4 and CD28 activated lymphocyte molecules are closely related in both mouse and human as to sequence, message expression, gene structure, and chromosomal location," J. Immunol. 147:1037-1044 (1991).
Linsley et al., "T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1," Proc. Natl. Sci. USA 87:5031-5025 (1990).
Freeman et al., "B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells," J. Immunol. 143:2714-2722 (1989).
Linsley et al., "CTLA-4 is a second receptor for the B-cell activation antigen B7," J. Exp. Med. 174:561-569 (1991).
Kaufman et al., "Cysteines in the Transmembrane Region of Major Histocompatibility Complex Antigens Are Fatty Acylated via Thioester Bonds," J. Biol. Chem. 259:7230-7238 (1984).
Rose et al., "The presence of cysteine in the cytoplasmic domain of the vesicular stomatitis virus glycoprotein is required for palmitate addition," Proc. Natl. Acad. Sci. USA 81:2050-2054 (1984).
Lemke et al., "Isolation and Analysis of the Gene Encoding Peripheral Myelin Protein Zero," Neuron 1:73-83 (1988).
Littman et al., "Unusual intron in the immunoglobulin domain of the newly isolated murine CD4 (L3T4) gene," Nature 325:453-455 (1987).
Owens et al., "Organization of the neural cell adhesion molecule (N-CAM) gene: alternative exon usage as the basis for different membrane-associated domains," Proc. Natl. Acad. Sci. USA 84:294-298 (1987).
Kasinrerk et al., "Human Leukocyte Activation Antigen M6, A Member of the Ig Superfamily . . . ," Journ. of Immunol. 149:847-854 (1992).
Wang et al., "Identification and Molecular Cloning of Tactile . . . ," Journ. of Immunol. 148:2600-2608 (1992).
Brunet et al., "A Differential Molecular Biology Search for Genes Preferentially Expressed in Functional T Lymphocytes . . . ," Immunol. Reviews, No. 103, p. 22-36 (1988).
Zhou et al., "A Novel Cell-Surface Molecule Expressed by Human Interdigitating Reticulum . . . ," Journ. of Immunol. 149:735-742 (1992).
King et al., "Mechanisms of Dendritic Cell Function," Bland-Sutton Institute, University College and Meddlesex School of Medicine 11(6) (1990).
Steinman, "The Dendritic Cell System and its Role in Immunogenicity," Annu. Rev. Immunol. 9:271-296 (1991).
Streilein et al., "Functional Dichotomy between Langerhans Cells that Present Antigen to Naive . . . ," Immunol. Reviews 117:160-183 (1990).
EMBL Database entry EBV, accession no VO1555 et al.; 1983; Epstein-Barr virus genome. *sequence*.

Affiliated with

Also associated with

Rating

Antibodies to lymphocyte activation antigens and uses therefor does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antibodies to lymphocyte activation antigens and uses therefor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibodies to lymphocyte activation antigens and uses therefor will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1909269