Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof
Patent
1997-04-10
1999-11-09
Johnson, Nancy A
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Monoclonal antibody or fragment thereof
4241521, 4241561, 4241781, 4241831, 435326, 435336, 53038824, 5303881, 5303917, 53038885, A61K 39395, C12N 512, C07K 1618, C07K 1624
Patent
active
059808942
ABSTRACT:
The invention relates to monoclonal antibodies to human leukemia inhibitory factor. The disclosed monoclonal antibodies are believed to recognize unique epitopes on hLIF and are useful in the treatment of conditions wherein the presence of hLIF causes or contributes to undesirable pathological effects, such as cachexia, dysregulated calcium metabolism, or excessive bone cell proliferation, and in the detection of hLIF, for example, in clinical samples or specimens.
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Conley Dierdre L.
Genentech Inc.
Johnson Nancy A
Johnston Sean A.
Torchia Timothy E.
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