Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2006-04-18
2006-04-18
Gambel, Phillip (Department: 1644)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C530S387900, C530S388100, C530S388200, C530S388220, C530S388700, C530S388730, C530S388750, C530S389100, C530S389600, C424S130100, C424S137100, C424S139100, C424S146100, C424S143100, C424S144100, C424S152100, C424S153100, C424S154100, C424S172100, C424S173100, C435S325000, C435S326000, C435S331000, C435S332000, C435S334000, C435S343000, C435S343100, C435S343200, C435S346000
Reexamination Certificate
active
07030225
ABSTRACT:
A cell surface molecule that is expressed specifically in thymocytes, lymphocytes activated by ConA-stimulation, and peripheral blood lymphocytes. This molecule is involved in signal transmission of the secondary signal (costimulatory signal) essential for the activation of lymphocytes such as T cells and regulates functions of activated lymphocytes such as activated T cells. Disclosed are an antibody or a portion thereof, which binds to a polypeptide of the cell surface molecule, a polypeptide fragment thereof, or a fusion polypeptide comprising the fragment; a cell secreting the antibody or its portion; a pharmaceutical composition comprising the antibody; and methods of using the compositions for therapeutic, diagnostic and/or experimental purpose.
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Tamatani Takuya
Tezuka Katsunari
Fish & Richardson P.C.
Gambel Phillip
Japan Tobacco Inc.
Ouspenski Ilia
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