Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2006-07-18
2006-07-18
Landsman, Robert S. (Department: 1647)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C530S387100, C530S388100, C530S388150, C530S389100, C435S007100
Reexamination Certificate
active
07078493
ABSTRACT:
The present inventors have discovered novel receptors in the Tumor Necrosis Factor (TNF) receptor family. In particular, receptors having homology to the type 2 TNF receptor (TNF-RII) are provided. Isolated nucleic acid molecules are also provided encoding the novel receptors of the present invention. Receptor polypeptides are further provided as are vectors, host cells and recombinant methods for producing the same.
REFERENCES:
patent: 5395760 (1995-03-01), Smith et al.
patent: 5464938 (1995-11-01), Smith et al.
patent: 5712155 (1998-01-01), Smith et al.
patent: 5741899 (1998-04-01), Capon et al.
patent: 6015938 (2000-01-01), Boyle et al.
patent: 6284485 (2001-09-01), Boyle et al.
patent: 6284728 (2001-09-01), Boyle et al.
patent: 6284740 (2001-09-01), Boyle et al.
patent: 6288032 (2001-09-01), Boyle et al.
patent: 6369027 (2002-04-01), Boyle et al.
patent: 0 585 939 (1994-03-01), None
patent: 0 816 380 (1998-01-01), None
patent: 0 816 380 (1998-01-01), None
patent: 0 897 114 (1999-02-01), None
patent: WO 91/09045 (1991-06-01), None
patent: WO 94/09137 (1994-04-01), None
patent: WO 94/13808 (1994-06-01), None
patent: WO 96/26217 (1996-08-01), None
patent: WO 96/26217 (1996-08-01), None
patent: WO 96/28546 (1996-09-01), None
patent: WO 96/28546 (1996-09-01), None
patent: WO 98/48051 (1998-10-01), None
Kohno, T. et al., “A second tumor necrosis factor receptor gene product can shed a naturally occurring tumor necrosis factor inhibitor,”Proc. Natl. Acad. Sci. USA 87:8331-8335 (1990).
Schall, T.J. et al., “Molecular Cloning and Expression of a Receptor for Human Tumor Necrosis Factor,”Cell 61:361-370 (1990).
Aruffo, A.A. et al., Database A-Geneseq24 on MASPAR, Accession No. R38859 (1993).
Aggarwal, B. B. and K. Natarajan, “Tumor necrosis factors: Developments during the last decade,”Eur. Cytokine Netw. 7(2):93-124 (Apr.-Jun. 1996).
Aslanidis, C., Database EMBL-new3 on MASPAR, Accession No. X75491 (Mar. 1994).
Beutler, B. et al., “Unraveling function in the TNF ligand and receptor families,”Science 264:667-668 (1994).
Bowie, J.U. et al., “Deciphering the message in protein sequences: tolerance to amino acid substitutions,”Science 247:1306-1310 (1990).
Camerini, D. et al., “The T Cell Activation Antigen CD27 Is a Member of the Nerve Growth Factor/Tumor Necrosis Factor Receptor Gene Family,”J. Immunol. 147(9):3165-3169 (1991).
Chinnaiyan, A.M. et al., “Signal Transduction by DR3, a Death Domain-Containing Receptor Related to TNFR-1 and CD95,”Science 274:990-992 (1996).
Crowe, P.D. et al., “A lymphotoxin-beta-specific receptor,”Science 264:707-710 (1994).
Dürkop, H. et al., “Molecular Cloning and Expression of a New Member of the Nerve Growth Factor Receptor Family That Is Characteristic for Hodgkin's Disease,”Cell 68:421-427 (1992).
Engelmann, H. et al., “Two Tumor Necrosis Factor-Binding Proteins Purified from Human Urine. Evidence for Immunological Cross-Reactivity with Cell Surface Tumor Necrosis Factor Receptors,”J. Biol. Chem. 265(3):1531-1536 (1990).
Feinstein, E. et al., “The death domain: a module shared by proteins with diverse cellular functions,”TIBS 20:342-344 (Sep. 1995).
Genexpress, Database EMBL/GenBank/DDBJ on MASPAR, Accession No. Z38433 (Oct. 1994).
George, et al., inMacromolecular Sequencing and Synthesis, Schlessinger, D.H., ed., Alan R. Liss, Inc., New York, pp. 127-149 (1988).
Glasgow, E. and Schechter, N., Database EMBL-new3 on MASPAR, Accession No. L23876 (1993).
Hillier, L. et al., Database EST-STS on MASPAR, Accession No. H14106 (Jul. 1995).
Himmler, A. et al., “Molecular Cloning and Expression of Human and Rat Tumor Necrosis Factor Receptor Chain (p60) and Its Soluble Derivative, Tumor Necrosis Factor-Binding Protein,”DNA and Cell Biol. 9(10):705-715 (1990).
Hohmann, H.-P. et al., “Two Different Cell Types Have Different Major Receptors for Human Tumor Necrosis Factor (TNFα)”J. Biol. Chem. 264(25):14927-14934 (1989).
Hsu, K. C. and M. V. Chao, “Differential Expression and Ligand Binding Properties of Tumor Necrosis Factor Receptor Chimeric Mutants,”J. Biol. Chem. 268(22):16430-16436 (1993).
Hudson, T., Database EST-STS on MASPAR, Accession No. G11923 (Oct. 1995).
Itoh, N. et al., “The Polypeptide Encoded by the cDNA for Human Cell Surface Antigen Fas Can Mediate Apoptosis,”Cell 66:233-243 (1991).
Johnson, D. et al., “Expression and Structure of the Human NGF Receptor,”Cell 47:545-554 (1986).
Lewis, M. et al., “Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific,”Proc. Natl. Acad. Sci. USA 88:2830-2834 (1991).
Loetscher, H. et al., “Molecular Cloning and Expression of the Human 55 kd Tumor Necrosis Factor Receptor,”Cell 61:351-359 (1990).
Mallett, S. et al., “Characterization of the MRC 0X40 antigen of activated CD4 positive T lymphocytes—a molecule related to nerve growth factor receptor ,”EMBO J. 9(4):1063-1068 (1990).
Muzio, M. et al., “FLICE, A Novel FADD-Homologous ICE/CED-3-like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex,”Cell 85:817-827 (1996).
NCBI Entrez, GenBank Report, Accession No. D62967, from Fujiwara, T. et al. (Aug. 1995).
NCBI Entrez, GenBank Report, Accession No. D63118, from Fujiwara, T. et al. (Aug. 1995).
NCBI Entrez, GenBank Report, Accession No. D63125, from Fujiwara, T. et al. (Aug. 1995).
NCBI Entrez, GenBank Report, Accession No. D63126, from Fujiwara, T. et al. (Aug. 1995).
NCBI Entrez, GenBank Report, Accession No. AA296905, from Adams, MD. et al. (Sep. 1995).
NCBI Entrez, GenBank Report, Accession No. AA296908, from Adams, M.D. et al. (Sep. 1995).
NCBI Entrez, GenBank Report, Accession No. 298429, from Adams, M.D. et al. (Sep. 1995).
NCBI Entrez, GenBank Report, Accession No. H88769, from Hillier, L. et al. (Nov. 1995).
NCBI Entrez, GenBank Report, Accession No. C02463, from Okubo, K. et al. (Jul. 1996).
NCBI Entrez, GenBank Report, Accession No. AA037313, from Hillier, L. et al. (Nov. 1996).
NCBI Entrez, GenBank Report, Accession No. AA195113, from Hillier, L. et al. (May 1997).
NCBI Entrez, GenBank Report, Accession No. AA233719, from Hillier, L. et al. (Aug. 1997).
NCBI Entrez, GenBank Report, Accession No. AA706996, from Hillier, L. et al. (Dec. 1997).
NCBI Entrez, GenBank Report, Accession No. AA599841, from Jia, L. et al. (Mar. 1998).
Nophar, Y. et al., “Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor,”EMBO J. 9(10):3269-3278 (1990).
Pfeffer, K. et al., “Mice Deficient for the 55 kd Tumor Necrosis Factor Receptor Are Resistant to Endotoxic Shock, yet Succumb to L. monocytogenes Infection,”Cell 73:457-467 (1993).
Piguet, P. F. et al., “Evolution of collagen arthritis in mice is arrested by treatment with anti-tumour necrosis factor (TNF) antibody or a recombinant soluble TNF receptor,”Immunol. 77:510-514 (1992).
Radeke, M. J. et al., “Gene transfer and molecular cloning of the rat nerve growth factor receptor,”Nature 325:593-597 (1987).
Salgaller, M.L. et al., “Generation of specific anti-melanoma reactivity by stimulation of human tumor-infiltrating lymphocytes with MAGE-1 synthetic peptide,”Cancer Immunol. Immunother. 39:105-116 (1994).
Smith, C.A. et al., “A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins,”Science 248:1019-1023 (1990).
Smith, C. A. et al., “T2 Open Reading Frame from the Shope Fibroma Virus Encodes a Soluble Form of the TNF Receptor,”Biochem. Biophys. Res. Comm. 176(1):335-342 (1991).
Stamenkovic, I. et al., “A B-lymphocyte activation molecule related to the nerve growth factor receptor
Fleischmann Robert D.
Greene John M.
Ni Jian
Human Genome Sciences Inc.
Human Genome Sciences Inc.
Jegatheesan Seharaseyon
Landsman Robert S.
LandOfFree
Antibodies to human tumor necrosis factor receptor-like genes does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antibodies to human tumor necrosis factor receptor-like genes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibodies to human tumor necrosis factor receptor-like genes will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3572252