Antibodies to human Ependymin

Details Antibodies to human Ependymin Antibodies to human Ependymin

2007-08-07

2007-08-07

Haddad, Maher M. (Department: 1644)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

Reexamination Certificate

active

10733646

ABSTRACT:
The present invention relates to a novel human Ependymin protein which is a member of the ependymin family. In particular, isolated nucleic acid molecules are provided encoding the human Ependymin protein. Ependymin polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of Ependymin activity. Also provided are diagnostic methods for detecting nervous system-related disorders and therapeutic methods for treating nervous system-related disorders.

REFERENCES:
patent: 5545719 (1996-08-01), Shashoua et al.
patent: 6489138 (2002-12-01), Ebner et al.
patent: 6613887 (2003-09-01), Ogi et al.
patent: 6683161 (2004-01-01), Ebner et al.
patent: 2004/0014947 (2004-01-01), Ogi et al.
patent: WO 98/11130 (1998-03-01), None
Adams et al. “Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence.” Nature 377 (Supp. 6547):3-17 (1995).
Hoffman, W. “Ependymins and their potential role in nuroplasticity and regeneration: calcium-binding meningeal glycoproteins of the cerebrospinal fluid and extracellular matrix.” Int. J. Biochem (26)5-607-619 (1994).
Genbank Accession No. AA131797, Hiller et al. (Nov. 27, 1996).
Genbank Accession No. AA131847, Hillier et al. (Nov. 27, 1996).
Genbank Accession No. AA157807, Hillier et al. (Dec. 16, 1996).
Genbank Accession No. AA209496, Hillier et al. (Jan. 29, 1997).
Genbank Accession No. AA322665, Adams et al., (Apr. 14, 1997).
Genbank Accession No. AA325686 Adams et al. (Apr. 20, 1997).
Genbank Accession No. AA420449, (Oct. 16, 1997).
Genbank Accession No. AA442737, Hillier et al. (Jun. 3, 1997).
Genbank Accession No. A659548, (Nov. 5, 1997).
Genbank Accession No. C04855, Tanaka et al. (Jul. 30, 1996).
Genbank Accession No. F05414, Auffray et al., (Feb. 19, 1995).
Genbank Accession No. N47444, Hillier et al. (Feb. 14, 1996).
Genbank Accession No. N47445, Hillier et al. (Feb. 14, 1996).
Genbank Accession No. N49194, Hillier et al. (Feb. 14, 1996).
Genbank Accession No. N50249, Hillier et al. (Feb. 14, 1996).
Genbank Accession No. N53580, Hillier et al. (Jan. 28, 1997).
Genbank Accession No. W02349, Hillier et al., (Apr. 18, 1996).
Genbank Accession No. W58404, Hillier et al. (Oct. 15, 1996).
Genbank Accession No. W58478 (Hillier et al.) (Oct. 15, 1996).
Ogi et al., “Human ependymin-like protein encoding Cdna” Sequence homology search in Geneseq Database, Accession No. V07200, Nov. 6, 1998.
Ogi et al., “Human ependymin-like protein” Nov. 6, 1998, Database :A—Geneseq—101002, Accession No: AAW51119, alignment SEQ ID No:2(1-224).
Ogi et al., “Human ependymin-like protein” Nov. 6, 1998, Database :A—Geneseq—101002, Accession No: AAW51119, alignment SEQ ID No:2(2-224).
Ogi et al., “Human ependymin-like protein” Nov. 6, 1998, Database :A—Geneseq—101002, Accession No: AAW51119, alignment SEQ ID No:2(38-224).
Ogi et al., “Human ependymin-like protein” Nov. 6, 1998, Database :A—Geneseq—101002, Accession No: AAW51119, alignment SEQ ID No:2(41-224).
Ogi et al., “Human ependymin-like protein” Nov. 6, 1998, Database :A—Geneseq—101002, Accession No: AAW51119, alignment SEQ ID No:2(1-174).
Ogi et al., “Human ependymin-like protein” Nov. 6, 1998, Database :A—Geneseq—101002, Accession No: AAW51119, alignment SEQ ID No:2(41-174).
Ogi et al., “Human ependymin-like protein” Nov. 6, 1998, Database :A—Geneseq—101002, Accession No: AAW51119, alignment SEQ ID No:2(1-9).
Ogi et al., “Human ependymin-like protein” Nov. 6, 1998, Database :A—Geneseq—101002, Accession No: AAW51119, alignment SEQ ID No:2(8-16).
Ogi et al., “Human ependymin-like protein” Nov. 6, 1998, Database :A—Geneseq—101002, Accession No: AAW51119, alignment SEQ ID No:2(19-27).
Ogi et al., “Human ependymin-like protein” Nov. 6, 1998, Database :A—Geneseq—101002, Accession No: AAW51119, alignment SEQ ID No:2(69-77).
Ogi et al., “Human ependymin-like protein” Nov. 6, 1998, Database :A—Geneseq—101002, Accession No: AAW51119, alignment SEQ ID No.2(86-107).
Ogi et al., “Human ependymin-like protein” Nov. 6, 1998, Database :A—Geneseq—101002, Accession No: AAW51119, alignment SEQ ID No:2(113-123).
Ogi et al., “Human ependymin-like protein” Nov. 6, 1998, Database :A—Geneseq—101002, Accession No: AAW51119, alignment SEQ ID No:2(131-139).
Ogi et al., “Human ependymin-like protein” Nov. 6, 1998, Database :A—Geneseq—101002, Accession No: AAW51119, alignment SEQ ID No:2(159-167).

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