Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1994-07-19
1995-12-12
Scheiner, Toni R.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 792, 436161, 436518, 436824, 5303871, G01N 3353, G01N 3002, G01N 33543, C07K 1600
Patent
active
054749018
ABSTRACT:
A novel polypeptide, designated plasma carboxypeptidase B (PCPB), has been purified from human plasma. It has been cloned from a human liver cDNA library using PCR amplification. Provided herein is nucleic acid encoding PCPB useful in diagnostics and in the recombinant preparation of PCPB. PCPB is used in the preparation and purification of antibodies thereto, in the purification of plasminogen, in the inhibition of plasminogen activation by t-PA in the presence of fibrinogen, and in diagnostic assays.
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Drayna Dennis T.
Eaton Dan L.
Duffy Patricia A.
Genentech Inc.
Hasak Janet E.
Scheiner Toni R.
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