Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1993-06-18
1996-01-02
Lacey, David L.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
53038825, 5303891, 5303893, 43524027, C07K 1528, C07K 1500, C12N 512
Patent
active
054809746
ABSTRACT:
A peptide-specific monoclonal antibody derived from an immunogenic peptide from the extracellular hydrophilic region of the human C5 a receptor (C5aR) is useful for blocking C5a from binding to C5aR.
REFERENCES:
Morgan, E. L. et al., J. Immunol, 151(1): 377-388, Jul. 1, 1993.
Oppermann, M. et al., Immunobiology, 186(1-2): 58, Oct. 28-31, 1992.
Gerard, N. P. et al, Nature, 349: 614-617, 14 Feb. 1991.
Embers, J. A. et al., J. Immunol, 148(10): 3165-3173, May 15, 1992.
Lerner, R. A., Nature, 299: 592-596, 1982.
Oppermann, M. et al., J. Immunol, 151(7): 3785-3794, Oct. 1, 1993.
Ember Julia A.
Hugli Tony E.
Morgan Edward L.
Lacey David L.
Loring Susan A.
The Scripps Research Institute
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