Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2007-05-15
2007-05-15
Martinell, James (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S070210, C530S387100, C530S387300, C530S388100
Reexamination Certificate
active
10866831
ABSTRACT:
The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
REFERENCES:
patent: WO 98/06846 (1998-02-01), None
patent: WO 00/73454 (2000-12-01), None
patent: WO 01/68848 (2001-09-01), None
GenBank Accession No. NM006811, Bossolasco et al., “Homo sapiens tumor differentially expressed 1 (TDE1), mRNA” (Jul. 20, 1999).
GenBank Accession No. Z97053, Ho, S., “Human DNA sequence from clone RP1-179M20 on chromosome 20 Contains a 3' end of a novel gene similar to cellular retinaldehyde-binding protein, the TDE1 gene (Tumour differentially expressed 1), the PKIG gene encoding protein kinase (cAMP-dependent, catalytic) inhibitor gamma, the 3' end of the ADA gene encoding adenosine deaminase, a putative novel gene, 2 CpG islands, ESTs, STSs and GSSs, complete sequence” (Apr. 9, 2001).
GenBank Accession No. AF164794, Gu et al., Homo sapiens Diff33 protein homolog mRNA, complete cds (Jul. 2, 1999).
Swissport Locus Q13530, Bossolasco et al., Tumor differentially expressed protein 1 (Transmembrane protein SBBI99) (Jul. 20, 1999).
Nimmrich et al., “Seven genes that are differentially transcribed in colorectal tumor cell lines,”Cancer Letters160(1):37-43 (Nov. 10, 2000).
Hu et al., “Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning,”PNAS97(17):9543-9548 (Aug. 15, 2000).
Bossolasco et al., “The HumanTDEGene Homologue: Localization to 20q13.1-13.3 and Variable Expression in Human Tumor Cell Lines and Tissue,”Molec. Carcinogenesis26:189-200 (1999).
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Florence Charles
Rosen Craig A.
Ruben Steven M.
Human Genome Sciences Inc.
Martinell James
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