Antibodies to a testis-specific differentiation-regulatory...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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C530S388100, C530S389100, C435S007100

Reexamination Certificate

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11192374

ABSTRACT:
A gene expressed specifically in the testis has been unexpectedly isolated in the course of studies of the expression of a gene encoding an unknown protein that triggers cell death. The isolated gene was a novel gene sequence that had no significant homologue in the database. This gene was also found to be involved in the regulation of differentiation in the testis and to encode a protein, Tesmin, which may regulate the differentiation of spermatogeneous cells into primary spermatocytes. Tesmin proteins are described herein, as are antibodies that bind to such proteins.

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