Antibodies to a polypeptide encoded by a nucleic acid over...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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C530S387700, C530S387100, C530S388100, C530S388150, C530S391100, C530S391300

Reexamination Certificate

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10063648

ABSTRACT:
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

REFERENCES:
patent: 5536637 (1996-07-01), Jacobs
patent: 5965397 (1999-10-01), Jacobs et al.
patent: 6025156 (2000-02-01), Gwynn et al.
patent: 6124433 (2000-09-01), Falb et al.
patent: 6156500 (2000-12-01), Falb
patent: 6162604 (2000-12-01), Jacob
patent: 6228582 (2001-05-01), Rodier et al.
patent: 6395306 (2002-05-01), Cui et al.
patent: 6414117 (2002-07-01), Levinson
patent: 6465185 (2002-10-01), Goldfine et al.
patent: 6498235 (2002-12-01), Sheppard et al.
patent: 6562343 (2003-05-01), Levinson
patent: 6645499 (2003-11-01), Lal et al.
patent: 6730502 (2004-05-01), Van Hijum et al.
patent: 6737522 (2004-05-01), Sundick et al.
patent: WO 97/38085 (1997-10-01), None
Pennica et al. WISP genes are members of the connective tissue growth factor family that are up-regulated in Wnt-1-transformed cells and aberrantly expressed in human colon tumors (1998), PNAS, vol. 95, pp. 14717-14722.
Sen et al. Aneuploidy and cancer (2000), Curr. Opinion in Oncology, vol. 12, pp. 82-88.
Haynes et al., Proteome analysis: Biological Assay or data archive? (1998), Electrophoresis, vol. 19, pp. 1862-1871.
Hu et al., Analysis of genomic and Proteomic Data using Advanced literature mining (2003), J. of Proteome Research, vol. 2, pp. 405-412.
Chen et al. Discordant Protein and mRNA Expression in Lung Adenocarcinomas (2002), Molecular and Cellular Proteomics, vol. 1, pp. 304-313.
Klein et al Selection for Genes Encoding Secreted Proteins and ReceptorsProc Natl. Acad. Sci., 93:7108-7113 (1996).
Database Search, DNA Sequence Alignments [BLASTN 2.2.1[Jul. 12, 2001], NCBI].
Database Search, Protein Sequence Alignments [BLASTN 2.2.1 [Jul. 12, 2001], NCBI].
Alberts, et al. 1994.Molecular Biology of the Cell, 3rd Edition, pp. 1216-1217. New York: Garland Publishing.
Fessler, et al. 2002. A genomic and proteomic analysis of activation of the human neutrophil by lipopolysaccharide and its mediation by p38 mitogen-activated protein kinase.The Journal of Biological Chemistry, 277(35):31291-31302.
Hanash, S. 2003. Making sense of microarray data to classify cancer.The Pharmacogenomics Journal, 3:308-311.
Hanash, S. Mar. 2005. Integrated global profiling of cancer.Nature Reviews, Applied Proteomics Collection, pp. 9-14.
Tokunaga, et al. 2000. Application of quantitative RT-PCR using “TaqMan” technology to evaluate the expression of CK 18 mRNA in various cell lines.J. Exp. Clin. Cancer Res., 19(3):375-381.
Allman, et al. 1996.Blood, vol. 87, No. 12, pp. 5257-5288.
Alberts, et al. 1994.Molecular Biology of the Cell, 3rd Edition, pp. 403-404, 453. New York: Garland Publishing.
Alberts, et al. 2002.Molecular Biology of the Cell 4th Edition, pp. 302, 363-364, 379, 435. New York: Garland Publishing.
Chen, et al. 2002. Discordant Protein and mRNA Expression in Lung Adenocarcinomas.Molecular&Cellular Proteomics 1.4, 304-313.
Fu, et al. 1996. Translational regulation of human p53 gene expression.The EMBO Journal, vol. 15, No. 16, pp. 4392-4401.
Gökmen-Polar, et al., Feb. 2001, Elevated Protein Kinase C βII Is an Early Promotive Event in Colon Carcinogenesis,Cancer Research, vol. 61, pp. 1375-1381.
Grimaldi, et al. 1989. The t(5;14) chromosomal translocation in a case of acute lymphocytic leukemia joins the interleukin-3 gene to the immunoglobulin heavy chain gene.Blood, 73(8):2081-2085.
Gygi, et al. Mar. 1999. Correlation between Protein and mRNA Abundance in Yeast.Molecular and Cellular Biology, 1720-1730.
Hancock, W. S. 2004. Do we have enough biomarkers?Journal of Proteome Research, 3(4):685.
Hanna, et al. Aug. 1999. HER-2
eu breast cancer predictive testing.Pathology Associates Medical Laboratories.
Haynes, et al., 1998. Proteome analysis: Biological assay or data archive?Electrophoresis, vol. 19, pp. 1862-1871.
Hu, et al. 2003. Analysis of Genomic and Proteomic Data Using Advanced Literature Mining.Journal of Proteome Research, vol. 2, pp. 405-412.
Hyman et al. Nov. 2002. Impact of DNA Amplication of Gene Expression Patterns.Cancer Research, 62:6240-6245.
Jang A. Hill RP, Sep. 1997. An examination of the effects of hypoxia, acidosis, and glucose starvation on the expression of metastasis-associated genes in murine tumor cells.Clin. Exp. Metastasis 15(5): pp. 469-483.
Konopka, et al. Jun. 1986. Variable Expression of the Translocated c-abl Oncogene in Philadelphia-Chromosome-Positive B-Lymphoid Cell Lines from Chronic Myelogenous Leukemia Patients,National Academy of Sciences of the United States of America, vol. 83, No. 11, pp. 4049-4052.
Lewin, B. 1994. Oncogenes: Gene Expression and Cancer, Chap. 39, pp. 1196-1201.Genes V. New York: Oxford University Press.
Lewin, B. 1997. Regulation of Transcription, Chap. 29, pp. 847-848.Genes VI. New York: Oxford University Press.
Meeker, et al. 1990. Activation of the interleukin-3 gene by chromosome translocation in acute lymphocytic leukemia with eosinophilia.Blood, 76(2):285-289.
Meric, et al. 2002. Translation initiation in cancer: A novel target for therapy.Molecular Cancer Therapeutics, 1:971-979.
Ohara, et al. 2001. Directional cDNA library construction assisted by the in vitro recombination reaction.Nucleic Acids Research, vol. 29, No. e22, pp. 1-8.
Ørntoft, et al. 2002. Genome-wide study of gene copy numbers, transcripts, and protein levels in pairs of non-invasive and invasive human transitional cell carcinomas.Molecular&Cellular Proteomics, 1:37-45.
Pollack, et al. 2002. Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors.PNAS, 99(20):12963-12968.
Powell, et al. Oct. 1998. Expression of cytochrome P4502E1 in human liver: assessment by mRNA, genotype and phenotype.Pharmacogenetics, vol. 5: pp. 411-421.
Singleton, et al. 1992. Clinical and pathologic significance of the c-erbB-2 (HER-2
eu) oncogene.Pathol. Annu, 1(27):165-190.
Vallejo, et al. Dec. 2000. Evidence of tissue-specific, post-transcriptional regulation of NRF-2 expression.Biochimie82(12): 1129-33.
Wang, et al. 1996. mRNA differential display: Application in the discovery of novel pharmacological targets.TIPS, 17:276-279.
Zhigang, et al. 2004. Prostate stem cell antigen (PSCA) expression in human prostate cancer tissues and its potential role in prostate carcinogenesis and progression of prostate cancer.World Journal of Surgical Oncology, 2:13.
2002-2003 Catalog & Technical Reference, New England BioLabs, Inc., p. 122.
Abe, et al. “An increased high-mobility group A2 expression level is associated with malignant phenotype in pancreatic exocrine tissue.”Br J Cancer. Dec. 1, 2003;89(11):2104-9. (Abstract Only).
Anderson, et al. 1997. A comparison of selected mRNA and protein abundances in human liver.Electrophoresis, 18:533-537.
Ando, et al. “Selective apoptosis of natural killer-cell tumours by l-asparaginase.”Br. J. Haematol. Sep. 2005;130(6):860-8. (Abstract Only).
Aust, et al. “Human thyroid carcinoma cell lines and normal thyrocytes: expression and regulation of matrix metalloproteinase-1 and tissue matrix metalloproteinase inhibitor-1 messenger-RNA and protein.”Thyroid. Oct. 1997;7(5):713-24. (Abstract Only).
Barnes, et al. “Expression of embryonic fibronectin isoform EIIIA parallels alpha-smooth muscle actin in maturing and diseased kidney.”J. Histochem Cytochem. Jun. 1999;47(6):787-98. (Abstract Only).
Bea, et al. “BMI-1 gene amplification and overexpression in hematological malignancies occur mainly in mantle cell lymphomas.”Cancer Res. Mar 15, 2001;61(6):2409-12. (Abstract Only).
Blaschke, et al. “Rapid quantitation of proinflammatory and

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