Antibodies that recognize hyperproliferative cells and...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C530S387700, C530S388100, C424S184100

Reexamination Certificate

active

07446178

ABSTRACT:
The invention relates to antibodies that bind to antigens, such as antigens associated with hyperproliferating cells, and methods of treating hyperproliferative disorders. The invention antibodies are useful for treating hyperproliferative disorders, such as neoplasia.

REFERENCES:
patent: 5286647 (1994-02-01), Handley et al.
patent: WO-97-39774 (1997-10-01), None
patent: WO-99-43815 (1999-09-01), None
William E. Paul, ed., 3rd ed. 1993, Fundamental Immunology, p. 242.
Bowie (Science, 1990, 257:1306-1310).
Burgess et al ( J of Cell Bio. 111:2129-2138, 1990).
Tao. et al. The Journal of Immunology, 1989, 143(8): 2595-2601.
Gillies et al. Human Antibodies and Hybridomas, 1990, 1(1): 47-54).
Glassy, M.C. et al., “Requirements for human antibody cocktails for oncology,” Exp. Op. Biol. Ther. 5(10):1333-1338 (2005).
Mukerjee, S. et al., “Co-expression of tumor antigens and their modulation by pleiotrophic modifiers enhance targeting of human monoclonal antibodies to pancreatic carcinoma,” Human Antibodies 9:9-22 (1999).
Mukerjee, S. et al., “Characterization of human IgG1 monoclonal antibody against gangliosides expressed on tumor cells,” Hybridoma 17(2):133-142 (1998).
Yano, Y. et al., “Immunohistological Characterization of Human Monoclonal Antibody Against Lung Cancer,” J. Surgical Oncol. 39:108-113 (1988).
EP 03752346 Supplementary European Search Report dated Nov. 21, 2007.
Apantaku, L.M., “Breast cancer diagnosis and screening,” American Family Physician Aug. 1, 2000,; 62(3):596-602, 605-6. (Electronic version downloaded from http://www.healthlibrary.com/doctors2/breastcancer2.html.
Buskens, C. et al., “Adenocarcinomas of the Gastro-Esophageal Junction: A Comparative Study of the Gastric Cardia and the Esophagus with Respect to Cyclooxygenase-2 Expression,” Digestive Disease Week Abstracts and Itinerary Planner, vol. 2003, abstract No. 850, 2003, e-file.
Cotterchio, M. et al., “Ontario Familial Colon Cancer Registry: Methods and First-year Response Rates,” Chronic Diseases in Canada vol. 21, No. 2, 2000 (electronic version downloaded from http://www.phac-aspc.gc.ca/publicat/cdic-mcc/21-2/f—e.html.
Gura, T., “Systems for Identifying New Drugs Are Often Faulty,” Science vol. 278:1041-1042, Nov. 7, 1997.
Karaczyn, A. et al., “The Octapeptidic End of the C-Terminal Tail of Histone H2A Is Cleaved Off in Cells Exposed to Carcinogenic Nickel (II),” Chem. Res. Toxicol. 16:1555-1559 (2003).
Martin, A. and Weber, B.L., “Genetic and Hormonal Risk Factors in Breast Cancer,” J. of the National Cancer Inst., vol. 92, No. 14, Jul. 19, 2000.
Mylonas, M. et al., “An extremely stable Ni(II) complex derived from the hydrolytic cleavage of the C-terminal tail of histone H2A,” J. Inorg. Biochem. 99:637-643 (2005).
White, C.A., et al., “Antibody-Targeted Immunotherapy for Treatment of Malignancy,” Annu. Rev. Med. 2001, 52:125-45.
Oct. 2005, “Temporary protocol of treatment: Trastuzumab (Herceptin®) in adjuvant conditions,” Institu National de Cancer and Agence francaise de securite sanitaire des produits de sante, www.e-cancer.fr/medias/pttdefeng2710.pdf.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Antibodies that recognize hyperproliferative cells and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antibodies that recognize hyperproliferative cells and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibodies that recognize hyperproliferative cells and... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4040486

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.