Antibodies that recognize and bind phosphorylated human...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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C530S388100, C530S389100, C435S007210, C424S130100

Reexamination Certificate

active

06995243

ABSTRACT:
A molecule containing the antigen binding portion of an antibody specific for human glucocorticoid receptor phosphorylated at residue Ser211, Ser226 or Ser203 is obtained and a method of determining the presence of activated glucocorticoid receptors in cells from human glucocorticoid responsive tissue and a method of screening for a glucocorticoid agonist using the molecule, which is preferably an antibody, are provided in the present invention.

REFERENCES:
Wang et al., J. Biol. Chem., vol. 277, Issue 29, 26573-26580, Jul. 19, 2002.

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