Antibodies that bind to a ligand-induced binding site on GPIIIa

Details Antibodies that bind to a ligand-induced binding site on GPIIIa Antibodies that bind to a ligand-induced binding site on GPIIIa

1993-10-04

1995-11-28

Lacey, David L.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

5303882, 53038822, 53038825, 53038835, C12N 512, C07K 1618, C07K 1628

Patent

active

054707382

ABSTRACT:
An antibody that immunoreacts with a ligand-induced binding site (LIBS) on GPIIIa, and particularly, a LIBS induced in a platelet-associated GPIIb-IIIa/fibrinogen complex is disclosed. Further disclosed are diagnostic systems and methods for assaying LIBS-containing platelets in a vascular fluid sample using the antibodies of the invention.

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