Antibodies that bind to a ligand-induced binding site on GPIIIa

Details Antibodies that bind to a ligand-induced binding site on GPIIIa Antibodies that bind to a ligand-induced binding site on GPIIIa

1989-10-05

1994-02-08

Kepplinger, Esther L.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

436 69, 436504, 436548, 436811, 5303887, G01N 33567

Patent

active

052847519

ABSTRACT:
An antibody that immunoreacts with a ligand-induced binding site (LIBS) on GPIIIa, and particularly, a LIBS induced in a platelet-associated GPIIb-IIIa/fibrinogen complex is disclosed. Further disclosed are diagnostic systems and methods for assaying LIBS-containing platelets in a vascular fluid sample using the antibodies of the invention.

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