Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2008-04-08
2008-04-08
Romeo, David S (Department: 1647)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C530S387300, C530S388100, C530S389100, C530S391300, C530S388220
Reexamination Certificate
active
10145127
ABSTRACT:
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
REFERENCES:
patent: 5536637 (1996-07-01), Jacobs
patent: 5556767 (1996-09-01), Rosen et al.
Haynes et al. Proteome analysis: biological assay or data archive? Electrophoresis. Aug. 1998;19(11):1862-71.
Hancock WS. Do we have enough biomarkers? J Proteome Res. Jul.-Aug. 2004;3(4):685.
Hu et al. Analysis of genomic and proteomic data using advanced literature mining. J Proteome Res. Jul.-Aug. 2003;2(4):405-12.
Wang et al. mRNA differential display: application in the discovery of novel pharmacological targets. Trends Pharmacol Sci. Aug. 1996;17(8):276-9.
Henikoff et al. Gene families: the taxonomy of protein paralogs and chimeras. Science. Oct. 24, 1997;278(5338):609-14.
Saito-Hisaminato et al. Genome-wide profiling of gene expression in 29 normal human tissues with a cDNA microarray. DNA Res. Apr. 30, 2002;9(2):35-45.
Allman et al. BCL-6 expression during B-cell activation. Blood. Jun. 15, 1996;87(12):5257-68.
Chen et al. Discordant protein and mRNA expression in lung adenocarcinomas. Mol Cell Proteomics. Apr. 2002;1(4):304-13.
Bustin et al. The value of microarray techniques for quantitative gene profiling in molecular diagnostics. Trends Mol Med. Jun. 2002;8(6):269-72.
Klein et al. Selection for Genes Encoding Secreted Proteins and Receptors.Proc. Natl. Acad. Sci., 93:7108-7113 (1996).
Database Search, DNA Sequence Alignments [BLASTN 2.2.1 [Jul. 12, 2001], NCBI].
Database Search, Protein Sequence Alignments [BLASTP 2.2.1 [Jul. 12, 2001], NCBI].
Dayhoff, Accession No. P—AAU12274, WO 200140466-A2, Pub Date: Jun. 7, 2001, K. P. Baker et al.
Dayhoff, Accession No. CAB66788.1, Direct Submission, Submitted: Sep. 22, 2004, A. Poutska et al.
Dayhoff, Accession No. NP—112186.1, Genome Research 13 (10), 2265-2270, 2003, H.F. Clark et al.
Dayhoff, Accession No. AAH22027.1, Direct Submission, Submitted: Jan. 22, 2002, R. Strausberg et al.
GenBank, Accession No. P—AAA59308, WO 200043525-A2, Pub Date: Jul. 27, 2000, D. P. Cerretti.
GenBank, Accession No. AF171933, Biochem. Biophys. Res. Commun. 263 (3), 810-815, 1999, D. P. Cerretti et al.
GenBank, Accession No. P—AAS21346, WO 200140466-A2, Pub Date: Jun. 7, 2001, K. P. Baker et al.
GenBank, Accession No. HSM801822, Direct Submission, Submitted: Sep. 22, 2004, A Poustka et al.
GenBank, Accession No. AX086821, WO 0112659-A, Pub Date: Feb. 22, 2001, S. Weimann.
GenBank, Accession No. NM—030924, Genome Res. 13 (10), 2265-2270, 2003, H. F. Clark et al.
GenBank, Accession No. BC022027, Proc. Natl. Acad. Sci. USA 99 (26), 16899-16903, 2002, R. L. Strausberg et al.
Beer, D.G., et al., “Gene-Expression Profiled Predict Survival of Patients With Lung Adenocarcinoma,”Nature Medicine—8(8):816-824 (2002).
Golub, T.R., et al., “Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring,”Science—285:531-537 (1999).
Hedge et al., “A Concise Guide to cDNA Microarray Analysis”, BioTechniques, vol. 29, No. 3, pp. 548-562, Sep. 2000.
Wen, W., et al., “Comparison ofTP53Mutations Identified by Oligonucleotide Microarray and Conventional DNA Sequence Analysis1,”Cancer Research—60:2716-2722 (2000).
Abe, N., et al., “An Increased High-Mobility Group A2 Expression Level is Associated with malignant Phenotype in Pancreatic Exocrine Tissue,”Br J Cancer—89(11):2104-9 (2003) Abstract.
Ando, M., et al., “Selective Apoptosis of Natural Killer-Cell Tumours by I-Asparaginase,”Br J Haematol., —130(6):860-8 (2005) Abstract.
Aust, G., et al., “Human Thyroid Carcinoma Cell Lines and Normal Thyrocytes: Expression and Regulation of Matrix Metalloproteinase Inhibitor-1 Messenger-RNA and Protein,”Thyroid—7(5):713-24 (1997) Abstract.
Barnes, V.L., et al., “Expression of Embryonic Fibronectin Isoform EIIIA Parallels Alpha-Smooth Muscle Actin in Maturing and Diseased Kidney,”J Histochem Cytochem.—47(6):787-98 (1999) Abstract.
Bea, S., et al., “BMI-1 Gene Amplification and Overexpression in Hematological Malignancies Occur Mainly in Mantle Cell Lymphonas,”Cancer Res.—61(6):2409-12 (2001) Abstract.
Blaschke, V., et al., “Rapid Quantitation of Proinflammatory and Chemoattractant Cytokine Expression in Small Tissue Samples and Monocyte-Derived Dendritic Cells: Validation of a New Real-Time RT-PCR Technology,”J Immunol Methods.—246(1-2):79-90 (2000) Abstract.
Buckley, A.R., et al., “Butyrate-Induced Reversal of Dexamethasone Resistance in Autonomouse Rat Nb2 Lymphoma Cells,”Apoptosis.—2(6):518-28 (1997) Abstract.
Caberlotto, L. et al.,“Alterations in Neuropeptide Y Levels and Y1 Binding Sites in the Flinders Sensitive Line Rats, A Genetic Animal Model of Depression,”Neurosci Lett.—265(3):191-4 (1999) Abstract.
Caberlotto, L., et al., “Neurokinin 1 Receptor and Relative Abundance of the Short and Long Isoforms in the Human Brain,”Eur J Neurosci.—17(9):1736-46 (2003) Abstract.
Choi, D., et al., “Characterization of Cyclin D2 Expression in Human Endometrium,”J Soc Gynecol Investig.—9(1):41-6 (2002) Abstract.
Couvelard, A., et al., “Human Chorionic Gonadotrophin Beta Expression in Malignant Barrett's Oesophagus,”Virchows Arch.—445(3):279-84 (2004) Abstract.
Dagenais, A., et al., “Downregulation of EnaC Activity and Expression by TNF-Alpha in Alveolar Epithelial Cells,”Am J. Physio Lung Cell Mol Physiol.—286(2):L301-11 (2004) Abstract.
De Boer, C.J., et al., “Involement of the CCNDI Gene in Hairy Cell Leukemia,”Ann Oncol.—7(3):251-6 (1996) Abstract.
Debieve, F., et al., “Inhibin and Activin Production and Subunit Expression in Human Placental Cells Cultured in Vitro,”Mol Hum Reprod.—6(8):743-9 (2000) Abstract.
Dong, Z., et al., “Expression of Membrane-Type Matrix Metalloproteinases 4, 5, and 6 in Mouse Corneas Infected withP. Aeruginosa” Invest Opthalmol Vis Sci—42(13):3223- (2001) Abstract.
Duchrow, M., et al., “Assessment of Proliferative Activity in Colorectal Carcinomas by Quantitative Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR),”Cancer Invest.—19(6):588-96 (2001) Abstract.
Dyer, J., et al., “Molecular Characterisation of Carbohydrate Digestion and Absorption in Equine Small Intestine,”Equine Vet J.—34(4):349-58 (2002) Abstract.
Egwuagu, C.E., et al., “Suppressors of Cytokine Signaling Proteins are Differentially Expressed in Th1 and Th2 Cells: Implications for Th Cell Lineage Commitment and Maintenance,”J Immunol.—168(7):3181-7 (2002) Abstract.
El-Ghrably, I.A., et al., “Intravitreal Invading Cells Contribute to Vitreal Cytokine Milieu in Proliferative Vitreoretinopathy,”Br J Opthalmol.—85(4):461-70 (2001) Abstract.
Eleore, L., et al., “Modulation of the Glutamatergic Receptors (AMPA and NMDA) and of Glutamate Vesicular Transporter 2 in the Rat Facial Nucleus after Axotomy,”Neuroscience—136(1):147-60 (2005) Abstract.
Forsberg, H., et al., “Altered Levels of Scavenging Enzymes in Embryos Subjected to a Diabetic Environment,”Free Radic Res.—24(6):451-9 (1996) Abstract.
Freyschuss, B., et al., “Induction of the Estrogen Receptor by Growth Hormone and Glucocorticoid Substitution in Priminary Cultures of Rat Hepatocytes,”Endocrinology—133(4):1548-54 (1993) Abstract.
Fu, K., et al., “ Cyclin D1-Negative
Goddard Audrey
Godowski Paul J.
Gurney Austin L.
Smith Victoria
Wood William I.
Barnes Elizabeth M.
Dreger Ginger R.
Genentech Inc.
Kresnak Mark T.
Romeo David S
LandOfFree
Antibodies that bind PRO5005 Polypeptides does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antibodies that bind PRO5005 Polypeptides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibodies that bind PRO5005 Polypeptides will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3906959