Antibodies that bind M. tuberculosis polypeptides

Details Antibodies that bind M. tuberculosis polypeptides Antibodies that bind M. tuberculosis polypeptides

2003-01-15

2009-10-13

Swartz, Rodney P. (Department: 1645)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Binds antigen or epitope whose amino acid sequence is...

C424S130100, C424S141100, C424S150100, C424S164100, C424S168100, C424S248100, C530S300000, C530S350000

Reexamination Certificate

active

07601350

ABSTRACT:
Purified antibodies that bind toM. tuberculosisERP protein are disclosed. In one embodiment, a purified antibody, which binds specifically with a polypeptide comprising SEQ ID NO: 39 or SEQ ID NO: 41 is provided. In some embodiments the polypeptide has a theoretical molecular weight of about 28 kDa. In other embodiments the polypeptide has an observed molecular weight of about 36 kDa, as determined by denaturing polyacrylamide gel electrophoresis (SDS-PAGE). The purified antibody may be a monoclonal or a polyclonal antibody. Further embodiments provide antibodies that does not bind specifically withM. lepraeP28 protein. The antibodies of the invention have many uses including the identification ofM. tuberculosis.

REFERENCES:
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