Antibodies specifically recognizing somatotropin binding protein

Details Antibodies specifically recognizing somatotropin binding protein Antibodies specifically recognizing somatotropin binding protein

1995-06-05

1998-09-15

Feisee, Lila

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Monoclonal antibody or fragment thereof

4241981, 53038824, 5303879, 435 71, 4351722, 435331, 435332, 435336, A61K 3900, A61K 39395, G01N 3353, C07K 1600

Patent

active

058075500

ABSTRACT:
The present invention is directed to antibodies, in particular monoclonal antibodies, which specifically bind to somatotropin binding proteins of animals, but not with the corresponding somatotropin receptors. The antibodies may be used alone to enhance the growth of animals, or may be used together with somatotropin to potentiate the effect of somatotropin in animals. The antibodies may also be used to assay the level of somatotropin binding protein of animals.

REFERENCES:
Lerner, Nature 299:592-596, 1982.
Baumbach et al., Genes and Development 3(8):1199-1205, 1989.
Smith et al., Molecular Endocrinology 3(6):984-990, 1989.
Sevier et al., Clin. Chem. 27(11) :1979-1806, 1981.

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