Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...
Reexamination Certificate
2008-03-07
2010-06-01
Swartz, Rodney P. (Department: 1645)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
C424S130100, C424S139100, C424S141100, C424S142100, C424S150100, C424S163100, C424S164100, C424S184100, C424S185100, C424S190100, C435S007100, C530S300000, C530S350000
Reexamination Certificate
active
07727711
ABSTRACT:
Disclosed are antibodies that bind to the antigenic proteins GroES, RpIL, GroEL, SodB, UbiG, the ABC transporter, and an expressed antigenic protein of unknown function (the “BepA” protein) ofBartonella henselae, and use of these antigenic proteins in immunoassays in order to determine whether a sample from a subject contains one or more of these antibodies. Presence of such an antibody in the subject indicates that the subject is or was infected withBartonella henselae, or indicates that the subject has an increased likelihood of being infected presently or in the past withBartonella henselae. Also disclosed are kits for performing immunoassays, wherein each kit contains one or more of these antigenic proteins and also contains the reagents necessary for conducting an immunoassay.
REFERENCES:
patent: 2003/0235876 (2003-12-01), Bethke
Haake, D.A., et al. Heat shock response and groEL sequence ofBartonella henselaeandBartonella quintana. Microbiology, vol. 143, pp. 2807-2815, 1997.
Sander, A., et al. Serodiagnosis of cat scratch disease: Response toBartonella henselaein children and a review of diagnostic methods. Eur. J. Clin. Microbiol. Infect. Dis., vol. 20, pp. 393-401, 2001.
Adelson Martin E.
Loa Chien Chang
McCool Tera L.
Mordechai Eli
Lo, J.D. Siu K.
Medical Diagnostic Laboratories, LLC
Swartz Rodney P.
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