Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1994-06-14
1996-09-17
Scheiner, Toni R.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
4351722, 43524027, 435975, 436548, 5303883, C12Q 170, C12N 1506, C12N 512, C07K 1614
Patent
active
055567460
ABSTRACT:
The present invention is based upon the discovery of a group antigen common to various types of astroviruses and the production of polyclonal and monoclonal antibodies reactive with this group antigen. The present invention encompasses the polyclonal antibodies, monoclonal antibodies, hybridoma cell lines which produce these monoclonal antibodies, and methods of using the monoclonal antibodies for diagnosing and treating gastroenteritis.
REFERENCES:
patent: 4814268 (1989-03-01), Kreider et al.
Antibodies A Laboratory Manual, Harlow and Lane, Cold Spring Harbor Laboratory, pp. 210-213 (1988).
Abstracts of the Annual Meeting of the American Society for Microbiology "C-117-Hudson et al. Propagation of the Marin County Strain of Astrovirus and Its Detection by Monoclonal Antibody" p. 351 (May 1988).
Sevier et al "Monoclonal Anibodies in Clinical Immunology" clin Chem 27(11) pp. 1797-1806 (1981).
Kurtz, J. B. and T. W. Lee, Lancet, p. 1405 (Dec. 15, 1984).
Hudson, R. W., et al., Abstracts of the 1987 ICAAC, p. 99 #18.
Herrmann, J. E., et al., J. Infect. Dis., 158: 182-185 (1988).
Herrmann, J. E., et al., Abstracts of the 1989 ICAAC, p. 176 #454.
Blacklow Neil R.
Herrmann John E.
Scheiner Toni R.
University of Massachusetts Medical Center
Wortman Donna C.
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