Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1993-11-24
1995-12-12
Scheiner, Toni R.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435885, 435975, 436548, 5303884, 5303895, A61K 3574, G01N 3353, G01N 33569, G01N 33577
Patent
active
054749050
ABSTRACT:
The present invention relates to the isolation of newly discovered hemin/hemoglobin-binding proteins of Streptococcus pneumoniae with approximate molecular weights of 18, 43, 55, 66 and 76 kDa, respectively, thereby providing bacterial-derived antigens and active derivatives and parts thereof, useful in the diagnostic assays, vaccines and pharmaceutical compositions relative to these bacteria. In addition, the present invention is directed to polyclonal and monoclonal antibodies directed to the hemin/hemoglobin-binding proteins of Streptococcus pneumoniae. The present invention further relates to methods of diagnosing and treating human pneumococcal infections including kits therefor.
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Tai Stanley S.
Winter Ruth E.
Parsons Nancy J.
Research Corporation Technologies
Scheiner Toni R.
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