Antibodies specific for plasmacytoid dendritic cells

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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Details

C435S002000, C435S007210, C435S070210, C435S332000, C435S343000, C435S343100, C436S503000, C436S512000, C436S518000, C436S526000, C436S548000, C530S388200, C530S388700, C530S388730

Reexamination Certificate

active

06875580

ABSTRACT:
The invention provides immunological reagents (antibodies) capable of binding to plasmacytoid dendritic cells (pDC), to cell lines which express such antibodies and to a process for identifying and purifying plasmacytoid dendriticcells from tissues containing pDC using such antibodies.

REFERENCES:
Nakano et al., 2001. CD11c+B220+Gr-1+ cells in mouse lymp nodes and spleen display characteristics of plasmacytoid dendritic cells. Journal of Experimental Medicine 194: 1171-1178.*
Asselin-Paturel et al., 2003. Mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody. Journal of Immunology 171: 6466-6477.

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