Antibodies specific for N-terminal truncated and...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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C530S387300, C530S387900, C530S388150, C424S133100, C424S139100, C435S007100, C435S331000, C435S070210

Reexamination Certificate

active

08058405

ABSTRACT:
The present invention pertains to novel diagnostic assays for the diagnosis of amyloidosis, in particular Alzheimer's disease, and related aspects. In particular, monoclonal antibodies and an antibody assay are provided.

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Johnson-Wood K et al. Amyloid precursor protein processing and Abeta42 deposition in a transgenic mouse model of Alzheimer disease. Proc Natl Acad Sci USA, 1997; 94:1550-1555.
“Amyloid β ELISA Kits,” Product literature, Immuno-Biological Laboratories Co., Ltd., 2008, 1 page.
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Frenkel et al., “Generation of anti-β-amyloid antibodies via phage display technology”, Vaccine, 2004,22:2505-2508.
“For the Selective and Quantitative Measurement of Amyloid Beta x-40 and x-42 Peptides: —Monoclonal Antibodies —High Senstivity ELISA Kits, —Brain Tissue ELISA Kits”, The Genetics Company, Inc., Prospectus, Nov. 2008, pp. 1-16.

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