Antibodies specific for human pancreatitis associated protein

Details Antibodies specific for human pancreatitis associated protein Antibodies specific for human pancreatitis associated protein

1995-04-14

1999-09-28

Chan, Christina Y.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

4241391, 4241451, 4241521, 4241581, 424 91, 424 934, 435 71, 435 7021, 435331, 435332, 435336, 5303871, 5303881, 5303882, 53038824, 5303891, 5303892, A61K 39395, C07K 1618, C12N 512, G01N 3353

Patent

active

059590866

ABSTRACT:
The invention relates to the family of the protein (PAP) associated with acute pancreatitis in man and in the rat. It also relates to the nucleotide fragments coding for the above proteins. Also included in the framework of the invention are antibodies which recognize the PAP and which are capable of being used for the purpose of diagnosing pancreatitis. The invention also relates to the production of the PAP, in particular by genetic engineering.

REFERENCES:
patent: 5436169 (1995-07-01), Iovanna et al.
Scaver S. Genetic Engineering News 14(14):10 and 21, Aug. 1994.
Keim, V. and Loffler H.G. Clinical Physiology and Biochemistry 4(2):136-142, 1986.
Keim, V. et al. Gastroenterology 103(1):248-254, 1992.
Goding, J.W. "Monoclonal Antibodies: Priciples and Practice" 2nd ed. Academic Press, New York, 1986.
Reeck, G.R. et al. Cell 50:667, Aug. 1987.

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