Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1998-10-23
2000-08-01
Kemmerer, Elizabeth
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
5303871, 5303879, 5303881, 53038815, 53038824, 5303891, 5303892, C07K 1622, G01N 3353
Patent
active
060965061
ABSTRACT:
Growth differentiation factor-8 (GDF-8) is disclosed along with its polynucleotide sequence and amino acid sequence. Also disclosed are diagnostic and therapeutic methods of using the GDF-8 polypeptide and polynucleotide sequences.
REFERENCES:
patent: 5827733 (1998-10-01), Lee et al.
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Ngo et al. The Protein Folding Problem and Tertiary Structure Prediction. Merz et al., eds., Birkhauser, Boston, pp. 491-495, 1990
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Jones, et al., "Isolation of Vgr-2, a Novel Member of the Transforming Growth Factor-.beta.-Related Gene Family," Molecular Endocrinology vol. 6 No. 11, pp. 1961-1968, 1992.
Se-Jin Lee, "Expression of growth/differentiation factor 1 in the nervous system: Conservation of a bicistronic structure," Proc. Natl. Acad. Sci. USA vol. 88, pp. 4250-4254, May 1991.
Se-Jin Lee, "Identification of a Novel Member (GDF-1) of the Transforming Growth Factor-.beta. Superfamily," Molecular Endocrinology vol. 4, pp. 1034-1040, 1990.
Alexandra C. McPherron and Se-Jin Lee, "GDF-3 and GDF-9: Two New Members of the Transforming Growth Factor-.beta. Superfamily Containing a Novel Pattern of Cysteines," The Journal of Biological Chemistry, vol. 268, No. 5, pp. 3444-3449, 1993.
Lee Se-Jin
McPherron Alexandra C.
Haile Lisa A.
Kemmerer Elizabeth
The Johns Hopkins University School of Medicine
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