Antibodies reactive with normal and oncogenic forms of the ras p

Details Antibodies reactive with normal and oncogenic forms of the ras p Antibodies reactive with normal and oncogenic forms of the ras p

1991-11-27

1993-11-16

Lacey, David L.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

5303881, 5303897, 43524027, C07K 1528, C07K 1500, C12P 2108, C12N 512

Patent

active

052625230

ABSTRACT:
Antibodies reactive with normal and oncogenic forms of the ras p21 protein. The antibodies are secreted by hybridomas obtained by immunizing mice with the Ha ras p21 protein containing the arginine mutation at position 12 of the protein. The antibodies and immunoreactive fragments thereof of useful for detection, diagnosis, quantitation, staging and classification of normal and activated ras p21s in normal tissues, malignant and premalignant lesions.

REFERENCES:
patent: 5081230 (1992-07-01), Carney

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