Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Binds bacterium or component thereof or substance produced...
Reexamination Certificate
2011-03-08
2011-03-08
Navarro, Mark (Department: 1645)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Binds bacterium or component thereof or substance produced...
C424S130100, C424S141100, C424S150100, C424S178100, C424S179100, C424S183100, C424S246100, C424S278100
Reexamination Certificate
active
07901687
ABSTRACT:
The present invention relates to conjugates of oligosaccharides of formula 1, wherein R is a linker to a carrier protein and optionally comprises up to three further saccharides, 5 and which are useful for vaccination, methods of synthesis of such conjugates, antibodies against this antigen, hybridoma producing monoclonal antibodies against this antigen, assays using these antibodies for the detection ofB. anthracisspores and kits comprising these antibodies, and a vaccine for the prevention ofB. anthracisinfection comprising the conjugates of oligosaccharides of formula 1. Monoclonal antibodies 10 according to the invention selectively bind toB. anthracis, but not to related bacteria such asB. subtilis, B. cereusand other bacteria of this group such asB. thuringiensis.
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Pluschke Gerd
Seeberger Peter H.
Tamborrini Marco
Werz Daniel B.
Eth Zurich
Hines Ja'na
Navarro Mark
Schweizerisches Tropeninstitut
Wenderoth , Lind & Ponack, L.L.P.
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