Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,...
Reexamination Certificate
2008-07-15
2008-07-15
Salimi, Ali R. (Department: 1648)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
C435S345000
Reexamination Certificate
active
07399467
ABSTRACT:
The subject invention provides antibodies, including polyclonal and monoclonal antibodies, that bind to E6 proteins from at least three oncogenic strains of HPV. In general, the antibodies bind to amino acids motifs that are conserved between the E6 proteins of different HPV strains, particularly HPV strains 16 and 18. The subject antibodies may be used to detect HPV E6 protein in a sample, and, accordingly, the antibodies find use in a variety of diagnostic applications, including methods of diagnosing cancer. Kits for performing the subject methods and containing the subject antibodies are also provided.
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Belmares Michael P.
Diaz-Sarmiento Chamorro Somoza
Garman Jonathan David
Lu Peter S.
Schweizer Johannes
Arbor Vita Corporation
Salimi Ali R.
Wilson Sonsini Goodrich & Rosati
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