Antibodies for identifying and/or isolating at least one...

Details Antibodies for identifying and/or isolating at least one... Antibodies for identifying and/or isolating at least one...

2003-07-25

2009-06-02

Romeo, David S (Department: 1647)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Monoclonal antibody or fragment thereof

C424S143100, C530S388100, C530S388220

Reexamination Certificate

active

07541030

ABSTRACT:
The invention relates to monoclonal antibodies, or fragments thereof, for isolating and/or identifying at least one cell population which is selected from the group comprising haematopoietic stem cells, neuronal stem cells, neuronal progenitor cells, mesenchymal stem cells and mesenchymal progenitor cells. The antibodies, or fragments thereof, bind to an antigen which is the same as that bound by an antibody which is produced by the hybridoma cell lines CUB1, CUB2, CUB3 and CUB4, which were deposited in the DSMZ under the numbers DSM ACC2569, DSM ACC2566 and DSM ACC2565, on Aug, 14, 2002, and DSM ACC2551, on Dec. 7, 2002.

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Casset et al. (2003) BBRC 307, 198-205.
Conze, Tim et al., “CDCP1 is a novel marker for hematopoietic stem cells,” Ann. N.Y. Acad. Sci. (2003), 996:222-226.
Scherl-Mostageer M., et al., “Identification of a novel gene, CDCP1, overexpressed in human colorectal cancer,” Oncogene, (2001), 20: 4402-4408.
Yin, Amy H., et al. “AC133, a novel marker for human hematopoietic stem and progenitor cells” Blood, (1997) 90: 5002-5012.

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