Antibodies binding the TNF related protein, TNF-Y

Details Antibodies binding the TNF related protein, TNF-Y Antibodies binding the TNF related protein, TNF-Y

2008-09-23

2008-09-23

Saoud, Christine J (Department: 1647)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

C530S387100, C530S387700, C530S388100, C530S388150, C530S391100, C424S184100, C424S185100

Reexamination Certificate

active

11090448

ABSTRACT:
Nucleic acids encoding mammalian, e.g., primate or rodent, genes, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.

REFERENCES:
patent: 6277969 (2001-08-01), Le et al.
patent: WO 96/29411 (1996-09-01), None
Aderem and Ulevitch,Nature, 406(6797):782-787, Aug. 17, 2000. “Toll-like receptors in the induction of the innate immune response”.
Anderson and Van Itallie,Current Biology, 9(24):R922-4, Dec. 16, 1999. “Tight junctions: Closing in one the seal”.
Barrett, Kim E.,Baillieres Clin Gastroenterol., 10(1):Mar. 1-15, 1996. “Cytokines: sources, receptors and signalling”.
Bertini, R. et al.,J Exp Med., 189(11):1783-1789, Jun. 7, 1999. “Thioredoxin, a redox enzyme released in infection and inflammation, is a unique chemoattractant for neutrophils, monocytes, and T cells”.
Briscoe, J., et al.,Philos Trans R Soc Lond B Biol Sci. 351(1336):167-171, Feb. 29, 1996. “JAKs, STATs and signal transduction in response to the interferons and other cytokines”.
Choi, H-J, et al.,Nat Struct Biol., 5(5):400-406, May 1998. “Crystal structure of a novel human peroxidase enzyme at 2.0 Å resolution”.
Furuse, M., et al.,J Cell Biol., Nov. 15, 1999;147(4):891-903, Nov. 15, 1999. “Manner of interaction of heterogeneous claudin species within and between tight junction strands”.
Hirano, T. et al.,Genome Research, 10(5):659-663, May 2000. “Null mutation of PCLN-1/Claudin-16 results in bovine chronic interstitial nephritis”.
Ihle, J., et al.,Stem Cells, 15 (Suppl 1):105-111, 1997.“Jaks and Stats in cytokine signaling”.
Kawai, J., et al.,Database SWALL ‘Online!’, Accession No. Q9CQ18, Jun. 1, 2001. Definition: Functional annotation of a full-length mouse cDNA collection.
Levy, D.,Cytokine Growth Factor Rev., 8(1):81-90, Mar. 1997. “The house that JAK/STAT built”.
Locksley et al. (2001), ,Cell, 104:487-501 “The TNF and TNF Receptor Superfamilies: Integrating Mammalian Biology”.
Mendez, M.J., et al.,Nature Genetics, 15(2):146-156, Feb. 1997. “Functional “transplant”of megabase human immunoglobulin loci recapitulates human antibody response in mice”.
Morita, K., et al.,Proc Natl Acad Sci U S A, 96(2):511-516, Jan. 19, 1999. “Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands”.
Ngo et al., (1994)Computational Complexity, Protein Structure prediction, and the Levinthal Paradox, The Protein Folding Problem and Tertiary Structure Prediction, pp. 492-495.
Nielsen, H., et al.,Protein Engineering, 10(1):1-6, Jan. 1997. “Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites”.
Schwarz, D.A., et al.,Immunity, 9(5):657-668, Nov. 1998. “Schlafen, a new family of growth regulatory genes that affect thymocyte development”.
Silvennoinen, O., et al.,APMIS, 105(7):497-509, Jul. 1997. “Cytokine receptor signal transduction through Jak tyrosine kinases and Stat transcription factors”.
Simon, D.B., et al.,Science, 285(5424):103-106, Jul. 2, 1999. “Paracellin-1, a renal tight junction protein required for paracellular Mg2+ resorption”.
Wells, (1990),Biochemistry, 29(37):8509-8517 “Aditivity of Mutational Effects in Proteins”.
Winston and Hunter,Current Biology, 6(6):668-671, Jun. 1, 1996. “Intracellular signalling: Putting JAKs on the kinase MAP”.
Makhatadze (1998)Human Immunology59:571-579 “Tumor necrosis factor locus: genetic organization and biological implications”.
Vassalli (1992)Annu. Rev. Immunology10:411-452 “The pathophysiology of tumor necrosis factors”.

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