Antibodies and peptide antigens for producing antibodies...

Details Antibodies and peptide antigens for producing antibodies... Antibodies and peptide antigens for producing antibodies...

2005-01-04

2005-01-04

Chan, Christina (Department: 1644)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using tissue cell culture to make a protein or polypeptide

C435S007100, C435S331000, C530S388100, C530S388150, C530S388240, C530S389200, C530S327000, C530S412000, C530S413000

Reexamination Certificate

active

06838264

ABSTRACT:
Peptide antigens corresponding to amino acid residues 2-12, 1-12, 2-15 and 1-15 of parathyroid hormone (PTH), antibodies having an affinity to such peptide antigens and methods of producing the same. Such antigens, antibodies and methods producing the same according to the present invention are useful in determining bioactive intact PTH levels in serum, plasma, and/or cell culture media. Such antibodies further possess a high degree of species cross-reactivity, but substantially mitigated cross-reactivity to non-whole PTH peptide fragments and little to no recognition of the first amino acid residue of PTH.

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