Antibodies against type a botulinum neurotoxin

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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Details

C435S007100, C530S388100, C530S388200, C530S388400, C530S350000, C424S164100, C424S164100

Reexamination Certificate

active

07049085

ABSTRACT:
Antibodies for binding epitopes of BoNT/A and hybridomas which produce such antibodies are described. The antibodies of the present invention can be used in a method for detecting BoNT/A in a sample and/or in a method for purifying BoNT/A from an impure solution. In addition, the antibodies can be used for passive immunization against BoNT/A intoxication or as intoxication therapy. Another aspect of the invention is a kit for detecting BoNT/A in a sample.

REFERENCES:
Bavari et al. (Vaccine, 1998, vol. 16, No. 19, pp. 1850-1856).

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