Antibodies against monocyte chemotactic proteins

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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C530S388230, C530S387100, C530S387900, C530S387300

Reexamination Certificate

active

10855013

ABSTRACT:
The invention provides antibodies that bind to a plurality of β-chemokines, particularly monocyte chemotactic proteins MCP-1, MCP-2 and MCP-3. The invention also provides cells producing the antibodies, and methods of making and using the same.

REFERENCES:
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Anonymous: “Anti-human CCL7/MCP-3 Antibody,” R&D Systems, Inc.
Anonymous: “Antibodies to Cytokines & Cytokine Receptors,” Downloaded from the internet Mar. 12, 2007, according to the European Patent Office.
Dean, “Preparation and Characterization of Monoclonal Antibodies to Proteins and Other Cellular Components,”Methods in Molecular Biology, vol. 32:Basic Proteins and Peptide Protocols(1994).
Lummus et al., “Diisocyanate Antigen-enhanced Production of Monocyte Chemoattractant Protein-1, IL-8, and Tumor Necrosis Factor-a by Peripheral Mononuclear Cells of Workers with Occupational Asthma,”Journal of Allergy and Clinic Immunology, vol. 102(2):265-274, Aug. 1998.
Sawyer et al., “Methodology for Selection of Human Antibodies to Membrane Proteins from a Phage-Display Library,”Journal of Immunological Methods204:193-203 (1997).
European Supplemental Search Report of Application No. EP 02 792 310.1, dated Dec. 20, 2007.

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