Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2008-05-27
2008-05-27
Bunner, Bridget E. (Department: 1647)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C530S300000, C530S387300, C530S387900, C530S388220
Reexamination Certificate
active
07378503
ABSTRACT:
Antibodies which bind to IGF-IR and inhibit the binding of IGF-I and IGF-II to IGF-IR are characterized. These antibodies are implicated in anti-tumor therapy.
REFERENCES:
patent: 5770429 (1998-06-01), Lonberg et al.
patent: 7037498 (2006-05-01), Cohen et al.
patent: 2004/0018191 (2004-01-01), Wang et al.
patent: WO 87/05330 (1987-09-01), None
patent: WO 01/14424 (2001-03-01), None
patent: WO 02/053596 (2002-07-01), None
patent: WO 03/059951 (2003-07-01), None
patent: WO 03/100008 (2003-12-01), None
Jain, R.K., Vascular and interstitial barriers to delivery of therapeutic agents in tumors, 1990, Cancer and Metastasis Reviews, vol. 9, pp. 253-266.
Radikoff et al., Single amino acid substitution altering antigen-binding specificity, 1982, Proc. Natl. Acad. Sci. USA. vol. 79, pp. 1979-1983.
Dermer, G.R. Another anniversary for the war on cancer, 1994, Biotechnology, vol. 12, p. 320.
Coleman, P.M. Effects of amino acid sequence changes on antibody-antigen interactions, 1994, Research in Immunology, vol. 145, pp. 33-36.
S-L. Li et al, Cancer Immunology and Immunotherapy, vol. 49, No. 4/5, pp. 243-252, XP001113064 (2000).
M. Lubeck et al, The Journal of Immunology, vol. 135, No. 2, pp. 1299-1304 (1985).
Adams, T.E. et al, Cell. Mol. Life Sci. 57 (2000) 1050-1093.
Brüggemann, M. et al, J. Exp. Med. 166 (1987) 1351-1361.
Chen, J. et al, EMBO J. 12 (1993) 821-830.
Fishwild, D.M. et al, Nat. Biotechnol. 14 (1996) 845-851.
Lonberg, N. et al, Nature 368 (1994) 856-859.
Love, T.W. et al, Methods Enzymol. 178 (1989) 515-527.
Riechmann, L. et al, Nature 332 (1988) 323-327.
Schlaeger, E.-J., et al, Cytotechnology 30 (1999) 71-83.
Wilman, Prodrugs in Cancer Chemotherapy Biochemical Society Transactions, 14, 375-383, 615thMeeting Belfast (1986).
Graus Yvo
Kopetzki Erhard
Kuenkele Klaus-Peter
Mundigl Olaf
Parren Paul
Bunner Bridget E.
Dang Ian
Hoffmann-La Roche Inc.
Johnston George W.
Rocha-Tramaloni Patricia S.
LandOfFree
Antibodies against insulin-like growth factor 1 receptor and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antibodies against insulin-like growth factor 1 receptor and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibodies against insulin-like growth factor 1 receptor and... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2816117