Antibodies against cancer antigen TMEFF2 and uses thereof

Details Antibodies against cancer antigen TMEFF2 and uses thereof Antibodies against cancer antigen TMEFF2 and uses thereof

2007-10-30

2007-10-30

Foley, Shanon (Department: 1642)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Reexamination Certificate

active

10383447

ABSTRACT:
Described herein are methods and compositions that can be used for diagnosis and treatment of cancer.

REFERENCES:
Greenspan et al., Nature Biotechnology 7:936-937 (1999).
Bowie et al (Science, 1990, 257:1306-1310).
Gussow et al. (1991, Methods in Enzymology 203:99-121).
Rudikoff et al. (PNAS, USA, 1982, 79: 1979).
Uchida et al. (1999, Biochemical and Biophysical Research.
Gura (1997, Science 278:1041-1042).
Glynne-Jones et al., “TenB2, A Proteoglycan Identified in Prostate Cancer That is Associated with Disease Progression and Androgen Independence”,Int. J. Cancer, vol. 94, pp. 178-184 (2001).
Ford et al., “Identification of Differentially Expressed Genes Asociated with Recurrent Growth of Prostate Cancer”, J. of Urology, vol. 165, No. 5 Supplement, p. 138 (2001).
Afar et al., “Preclinical Validation of Anti-TMEFF2-Auristatin E-Conjugated Antibodies in the Treatment of Prostate Cancer”, Molecular Cancer Therapeutics, vol. 3, No. 8, pp. 921-932 (2004).

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