Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1989-04-28
1990-11-20
Griffin, Ronald W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514242, 4352521, 540485, 544320, A01N 4354, C12N 120, C07D22310, C07D23902
Patent
active
049719653
ABSTRACT:
Novel antibiotics TAN-1057 represented by the formula: ##STR1## wherein, the absolute configuration at (A) is R or S; R.sub.1 is hydrogen and both R.sub.2 and R.sub.3 taken together form a chemical bond, or R.sub.3 is hydrogen and both R.sub.1 and R.sub.2 taken together form a chemical bond; were produced by microorganisms belonging to the genus Flexibacter. TAN-1057 strongly inhibit the growth of pathogenic microorganisms and malignant tumors, thus being useful as therapeutic agents of infectious diseases or antitumor agents.
REFERENCES:
patent: 4258045 (1979-03-01), Poe et al.
patent: 4440765 (1981-04-01), Diamond et al.
patent: 4478839 (1982-10-01), Benneche et al.
patent: 4536504 (1985-08-01), Okutani
patent: 4772704 (1983-09-01), Algieri
Funabashi Yasunori
Harada Setsuo
Ono Hideo
Griffin Ronald W.
Takeda Chemical Industries Ltd.
Webber Pamela S.
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