Antibiotics PA-41746-B and C

Details Antibiotics PA-41746-B and C Antibiotics PA-41746-B and C

1982-09-29

1984-05-15

Lee, Mary C.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424274, 435119, C07D48704

Patent

active

044487231

ABSTRACT:
New antibiotics having .beta.-lactamase inhibitory activity, PA-41746-B and C of the formula ##STR1## wherein R is carboxymethylsulfinyl (PA-41746-B) or formylsulfinyl (PA-41746-C) and the pharmaceutically acceptable salts being useful as a medicament, a veterinary drug and a disinfectant for inhibiting the growth of gram-positive and gram-negative pathogenic microorganisms and a process for preparing the same, being characterized by cultivating Streptomyces pluracidomyceticus in a suitable medium and isolating PA-41746-B and/or PA-41746-C from the culture broth.

REFERENCES:
J. Antibiotics, vol. 35, p. 536 (1982).

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