Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1984-04-16
1985-10-22
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
2601125R, 514 25, 536 168, 536 181, A61K 3702, A61K 3171, C07H 1520
Patent
active
045489246
ABSTRACT:
Antibiotics M43B and M43C, new glycopeptide antibiotics of the vancomycin class, are produced by Nocardia orientalis NRRL 2452. M43B and M43C have antibacterial activity.
REFERENCES:
patent: 3067099 (1962-12-01), McCormick et al.
Donald J. McGraw, "The Antibiotic Discovery Era (1940-1960): Vancomycin as an Example of the Era", Thesis at Oregon State University, 1975, pp. 78-142.
F. J. Marshall, "Structure Studies on Vancomycin", J. Med. Chem. 8, 18-22, (1965).
G. M. Sheldrick et al., "Structure of Vancomycin and its Complex with Acetyl-D-alanyl-D-alanine", Nature 271, 223-225, (1978).
C. M. Harris, et al., "Structure of the Glucopeptide Antibiotic Vancomycin, Evidence for an Asparagine Residue in the Peptide", J. Am. Chem. Soc., 104, pp. 4293-4295.
"Vancomycin and Factor A", Report by Eli Lilly and Company sent to the U.S. Food and Drug Administration on Mar. 5, 1963.
G. K. Best et al., "Chromatographic Separation of the Vancomycin Complex", Antimicrob. Agents & Chemotherapy-1968, 115-119.
R. R. Pfeiffer, "Structural Features of Vancomycin", in Reviews of Infectious Diseases, vol. 3, Supplement (1981).
Brown Johnnie R.
Eli Lilly and Company
Harrison Nancy J.
Whale Arthur R.
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