Antibiotics, dexylosylbenanomicin B

Details Antibiotics, dexylosylbenanomicin B Antibiotics, dexylosylbenanomicin B

1991-06-14

1992-04-28

Lilling, Herbert J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 75, 435170, 4352521, 435826, 514 27, 536 172, 536 181, A61K 3170, C12P 1956

Patent

active

051091224

ABSTRACT:
Two new antibiotics which are now nominated as benanomicin A and benanomicin B, respectively, are fermentatively produced by the cultivation of a new microorganism, designated as MH193-16F4 strain, of Actinomycetes. Benanomicins A and B each show antifungal activity and are useful as a therapeutic antifungal agent. A new compound, dexylosylbenanomicin B is now produced by chemical conversion of benanomicin B, and this semi-synthetic antibiotic also shows antifungal activity and is useful as a therapeutic antifungal agent.

REFERENCES:
patent: 4870165 (1989-09-01), Oki et al.
patent: 4973673 (1990-11-01), Sawada et al.
patent: 4990497 (1991-02-01), Oki et al.
patent: 5055453 (1991-10-01), Takeuchi et al.
patent: 5061624 (1991-10-01), Sawada et al.

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