Antibiotics and process for preparation

Details Antibiotics and process for preparation Antibiotics and process for preparation

1995-04-11

1997-12-02

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540221, 514202, C07D50146, A61K 31545

Patent

active

056937911

ABSTRACT:
A group of reagents, as diisocyanates, dianhydrides, diacidchlorides, diepoxides, carbodiimides and the like are utilized to link a wide variety of antibiotic moities, reacted two at a time with said reagents, the said antibiotic moieties containing groups reactive with the linking reagents as carboxylic acid, alcolhol, primary amine, and secondary amine functional groups, said functional groups being present as singularities or as multiplicities, products being readily purified using chromatographic techniques, and said products of above reactions being valuable for the treatment of microbial infections of man and animals.

REFERENCES:
patent: 5180719 (1993-01-01), White et al.
patent: 5281703 (1994-01-01), White et al.
patent: 5336768 (1994-08-01), Albrecht et al.

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