Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...
Patent
1978-10-10
1983-01-11
Lee, Mary C.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Fungus, except allergen, or component thereof or substance...
2602452T, 435119, C07D48704, A61K 3140
Patent
active
043682030
ABSTRACT:
A novel antibiotic substance of the formula ##STR1## wherein R.sub.1 is CH.sub.3 and R.sub.2 is --CH.sub.2 --CH.sub.2 -- or R.sub.1 is H and R.sub.2 is --CH.dbd.CH--; and R.sub.3 represents hydrogen, lower alkyl or triphenylmethyl,
and including the salts of the compound of formula (I) wherein R.sub.3 is hydrogen, said antibiotic substance having strong antibiotic activity and .beta.-lactamase inhibiting effect, and a method for producing the same by aerobic cultivation of Streptomyces A271.
REFERENCES:
patent: 4235922 (1980-11-01), Ratcliffe et al.
Okamura et al.; Jour. of Antibiotics, vol. 31, No. 5 pp. 480-482, (5/78).
Fukagawa Yasuo
Hirata Shoji
Ishikura Tomoyuki
Kouno Kageaki
Lein Joseph
Lee Mary C.
Sanraku-Ocean Co., Ltd.
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