Antibiotics A6888C and A6888X

Details Antibiotics A6888C and A6888X Antibiotics A6888C and A6888X

1980-09-22

1982-11-09

Hazel, Blondel

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 76, 435886, C07H 1708

Patent

active

043585841

ABSTRACT:
Antibiotic compounds of the formula: ##STR1## wherein R' is ##STR2## or --CH.sub.2 OH, and the non-toxic pharmaceutically acceptable acid addition salts thereof, are produced by culturing Streptomyces flocculus NRRL 11459. Techniques for isolating the compounds are also described. Cirramycin A.sub.1 and cirramycin B are coproduced.

REFERENCES:
patent: 3159540 (1964-12-01), Kawaguchi et al.
patent: 3950516 (1976-04-01), Miyake
Omura et al., J. Antibiotics 28, 401-433, 1975.
Keller-Schierlein in Fortschritte der Chemie Organischer Naturstoffe, vol. 30, pp. 314-445.
Suzuki, Bull. Chem. Soc. Japan, vol. 48, p. 292, 1970.
Tsukira et al., J. Antibiotics, vol. 22, pp. 89-99, 1966.

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